Differences

This shows you the differences between two versions of the page.

--- home:food:alcohol [07.16.2009] – blockquote edits joyful
+++ home:food:alcohol [09.14.2022] (current) – external edit 127.0.0.1
@@ Line 1: / Line 1: @@
+====== Alcohol ======
+Patients with chronic inflammatory diseases often complain of alcohol intolerance. Sometimes a negative reaction is due to something other than the alcohol itself, such as the minute quantities of vitamin D in beer or the sulfites in wine. Alcohol consumption is not contraindicated for patients on the Marshall Protocol (MP).
+MP patients have reported that their tolerance for alcohol has improved after being on the MP.
+===== Binge drinking is immunosuppressive =====
+According to a 2009 //BMC Bioinformatics study//, binge drinking can weaken the body's ability to fight infections for at least 24 hours.(({{pmid>long:19765273}})) In experiments with mice, the researchers found that binge drinking affects toll-like receptor 4 (TLR4), a protein that plays an important role in immune system activation. Specifically, heavy drinking suppresses TLR4's ability to send signals that activate production of inflammatory cytokines – signaling molecules that begin the inflammatory response to infection.
+The researchers also determined that binge drinking inhibits NF-kappaB, a protein complex that controls DNA transcription and expression of some of the cytokines inhibited by alcohol.
+"The time frame [after binge drinking] during which the risk of infection is increased might be at least 24 hours," study author Stephen Pruett, of the College of Veterinary Medicine at Mississippi State University, said in a news release. "A persistent effect of ethanol on cells is indicated, such that inhibition of the response of some cytokines occurs even after the ethanol is cleared" from the body.
+===== Patient experiences =====
+<blockquote>
+I have absolutely no problem tolerating alcohol while on the protocol. I enjoy my wine with my evening meal.
+//**Guss Wilkinson**// </blockquote>
+<blockquote>
+I have a glass of plum wine every few days and sometimes a little brandy, so I doubt that a little alcohol with your minocycline is going to make you explode in a puff of smoke or anything like that.
+//**Trevor Marshall, PhD**// </blockquote>
+<blockquote>
+I was a regular "social drinker", wine mostly, prior to starting the MP and for about the first year I was on the MP.  Then, rather suddenly, I developed a real intolerance for alcoholic beverages.  My symptoms would come on on pretty quickly and occurred after consuming only modest amounts of alcohol.
+Now, I'm back to being able to enjoy an alcoholic beverage with no ill effects, but my intolerance probably lasted for a year.
+//**Carol**, MarshallProtocol.com// </blockquote>
+<blockquote>
+I would say this is a very individual thing.  I for one have such problems with dizziness that I avoid alcohol, and the sulfites in most wine make me quite ill. I sure miss that Irish whiskey and Guinness.  So count yourself as lucky if you can tolerate alcohol in moderation!
+//**P.B.**, MarshallProtocol.com// </blockquote>
+{{tag>Food_and_drink drinks}}
+<nodisp>
+===== Notes and comments =====
+  * Legacy content
+    * https://www.marshallprotocol.com/forum37/2753.html s351
+=====References=====
+</nodisp>

home/food/alcohol.txt · Last modified: 09.14.2022 by 127.0.0.1