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home:food:soy [01.03.2012] – external edit 127.0.0.1home:food:soy [09.14.2022] (current) – external edit 127.0.0.1
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 ===== Molecular effects of phytoestrogens found in soy ===== ===== Molecular effects of phytoestrogens found in soy =====
  
-{{ :home:food:genistein_black_small.jpg|genistein}}Soy is immunosuppressive, as it contains phytoestrogens such as genistein, which act directly on the Vitamin D Receptor.(({{pubmed>long:12710998}})) On the right is an image of genistein and 1,25-D as they dock into the VDR.+{{ :home:food:genistein_black_small.jpg|genistein}}Soy is immunosuppressive, as it contains phytoestrogens such as genistein, which act directly on the Vitamin D Receptor.(({{pmid>long:12710998}})) On the right is an image of genistein and 1,25-D as they dock into the VDR.
  
 For someone who is healthy, this is not a necessarily problem, but when one is ill with Th1 inflammation, the VDR is already compromised quite severely. For someone who is healthy, this is not a necessarily problem, but when one is ill with Th1 inflammation, the VDR is already compromised quite severely.
  
-Mitchell, //et. al.//, imply that only 40mg of isoflavones a day is likely to produce concentrations (about 500 nanomolar) capable of affecting the Vitamin D Receptor.(({{pubmed>long:11352776}})) This suggests that one need only consume 20 grams of roasted soyabeans - equivalent to 37mg of isoflavones - to have more than enough plasma concentration to further compromise the immune system.+Mitchell, //et. al.//, imply that only 40mg of isoflavones a day is likely to produce concentrations (about 500 nanomolar) capable of affecting the Vitamin D Receptor.(({{pmid>long:11352776}})) This suggests that one need only consume 20 grams of roasted soyabeans - equivalent to 37mg of isoflavones - to have more than enough plasma concentration to further compromise the immune system.
  
 Genistein interferes with the operation of at least three key nuclear receptors: the Vitamin D Receptor, the PPAR-gamma and PPAR-alpha. Genistein interferes with the operation of at least three key nuclear receptors: the Vitamin D Receptor, the PPAR-gamma and PPAR-alpha.
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 ===== Epidemiological impact of phytoestrogens ====== ===== Epidemiological impact of phytoestrogens ======
  
-The harmful effects of the phytoestrogens in soy has been observed in certain vegetarian populations. One British study concluded that "phytoestrogens have a deleterious effect on the developing male reproductive system,"(({{pubmed>long:10619956}})) including the increased risk of [[http://en.wikipedia.org/wiki/Hypospadias|hypospadias]].+The harmful effects of the phytoestrogens in soy has been observed in certain vegetarian populations. One British study concluded that "phytoestrogens have a deleterious effect on the developing male reproductive system,"(({{pmid>long:10619956}})) including the increased risk of [[https://en.wikipedia.org/wiki/Hypospadias|hypospadias]].
  
-Researchers at Loughborough University in England recently published two studies in the journal //Dementias// and in //Geriatric Cognitive Disorders// which found that eating high levels of some soy products may raise the risk of memory loss.(({{pubmed>long:18583909}}))+Researchers at Loughborough University in England recently published two studies in the journal //Dementias// and in //Geriatric Cognitive Disorders// which found that eating high levels of some soy products may raise the risk of memory loss.(({{pmid>long:18583909}}))
  
 The research team, led by Professor Ef Hogervorst, tracked soy intake and subsequent memory function in 719 elderly Indonesians living in urban and rural regions of the island of Java. They found high tofu consumption - at least once a day - was associated with worse memory, particularly among subjects over 68 years of age.  The research team, led by Professor Ef Hogervorst, tracked soy intake and subsequent memory function in 719 elderly Indonesians living in urban and rural regions of the island of Java. They found high tofu consumption - at least once a day - was associated with worse memory, particularly among subjects over 68 years of age. 
 ===== Read more ===== ===== Read more =====
  
-  * [[http://bacteriality.com/2008/07/15/tofu/|High tofu intake correlated with memory loss]] <html>&nbsp;</html> [[http://bacteriality.com|{{:home:bacteriality.gif}}]] +  * [[https://bacteriality.com/2008/07/15/tofu/|High tofu intake correlated with memory loss]] <html>&nbsp;</html> [[https://bacteriality.com|{{:home:bacteriality.gif}}]] 
-  * [[http://bacteriality.com/2008/03/21/soy/|Notre Dame researchers confirm the effect of soy on the Vitamin D Receptor]] <html>&nbsp;</html> [[http://bacteriality.com|{{:home:bacteriality.gif}}]] +  * [[https://bacteriality.com/2008/03/21/soy/|Notre Dame researchers confirm the effect of soy on the Vitamin D Receptor]] <html>&nbsp;</html> [[https://bacteriality.com|{{:home:bacteriality.gif}}]]
-{{tag>foods_to_avoid foods immunosuppressants}}+
  
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 +{{tag>Food_and_drink foods_to_avoid foods immunosuppressants}}
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 +<nodisp>
 ===== Notes and comments ===== ===== Notes and comments =====
    
  
  * Legacy content  * Legacy content
-    * http://www.marshallprotocol.com/view_topic.php?id=2434&forum_id=2&jump_to=90282#p90282 e187+    * https://www.marshallprotocol.com/view_topic.php?id=2434&forum_id=2&jump_to=90282#p90282 e187
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-===== References =====+===== References =====</nodisp> 
home/food/soy.txt · Last modified: 09.14.2022 by 127.0.0.1
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