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home:mp:stages:stagefive [10.22.2016] – [Antibiotics] sallieq | home:mp:stages:stagefive [07.24.2020] – [Antibiotics] sallieq | ||
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The Marshall Protocol (MP) activates the immune system in order to kill the microbiota of intraphagocytic bacteria which causes chronic inflammatory disease. The result of the MP's immune activation is increased symptoms due to immunopathology reactions. As immune function is restored, bacteria are killed and symptoms of disease tend to wane. While a patient may be feeling better over all, there is a danger of sudden increases in immunopathology known as an over-exuberant Stage Five reaction. | The Marshall Protocol (MP) activates the immune system in order to kill the microbiota of intraphagocytic bacteria which causes chronic inflammatory disease. The result of the MP's immune activation is increased symptoms due to immunopathology reactions. As immune function is restored, bacteria are killed and symptoms of disease tend to wane. While a patient may be feeling better over all, there is a danger of sudden increases in immunopathology known as an over-exuberant Stage Five reaction. | ||
- | An over-exuberant Stage Five reaction can happen in latter stages of the MP, even in the absence of antibiotics, | + | An over-exuberant Stage Five reaction can happen in latter stages of the MP, even in the absence of antibiotics, |
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+ | A Stage Five reaction is often erratic and may not be easily relieved by the usual techniques. | ||
An over-exuberant Stage Five response can be managed through increasing the dosing or frequency of olmesartan, adjusting antibiotics, | An over-exuberant Stage Five response can be managed through increasing the dosing or frequency of olmesartan, adjusting antibiotics, | ||
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When a patient' | When a patient' | ||
- | discontinue azithromycin if it has been taken. //N.B. the use of azithromycin is now strongly discouraged// | + | discontinue azithromycin if it has been taken. //**N.B. the use of azithromycin is now strongly discouraged**//. |
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+ | This will often result in a one-time exacerbation of symptoms, particularly from days 10 to 12 (and possibly even for some weeks), as the concentration of the azithromycin slowly wanes, but in the long run will lead to greater stability. | ||
Progressively withdrawing minocycline and clindamycin, | Progressively withdrawing minocycline and clindamycin, | ||
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