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home:mp:stages [07.18.2015] – [Stage 2: Unhealthy VDR, pathogens downregulate immune activity] sallieq | home:mp:stages [07.18.2015] – [Stage 2: Unhealthy VDR, pathogens downregulate immune activity] joyful | ||
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The body responds by increasing production of 1,25-D. While some 1,25-D activates the VDR, a lot does not, because the VDR is blocked by bacterial ligands and the body is never able to completely out-compete the production of bacterial substances. | The body responds by increasing production of 1,25-D. While some 1,25-D activates the VDR, a lot does not, because the VDR is blocked by bacterial ligands and the body is never able to completely out-compete the production of bacterial substances. | ||
- | The increase in 1,25-D introduces a new problem entirely. When 1,25-D reaches higher and higher levels, it begins to interfere with the activity | + | The increase in 1,25-D introduces a new problem entirely. When 1,25-D reaches higher and higher levels, it begins to interfere with important activities |