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home:mp:stages [07.18.2015] – [Stage 2: Unhealthy VDR, pathogens downregulate immune activity] joyfulhome:mp:stages [10.13.2018] – [Read more] sallieq
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 The body responds by increasing production of 1,25-D. While some 1,25-D activates the VDR, a lot does not, because the VDR is blocked by bacterial ligands and the body is never able to completely out-compete the production of bacterial substances. The body responds by increasing production of 1,25-D. While some 1,25-D activates the VDR, a lot does not, because the VDR is blocked by bacterial ligands and the body is never able to completely out-compete the production of bacterial substances.
  
-The increase in 1,25-D introduces a new problem entirely. When 1,25-D reaches higher and higher levels, it begins to interfere with the activity of important nuclear receptors other than the VDR. While 1,25-D is the activating hormone for the VDR, at high enough levels it binds to and inactivates other receptors. Like the VDR, these receptors have a role in innate immune function, but they also transcribe genes that lead to production of hormones of their own such as thyroid hormones and the sex hormones. This is why high levels of 1,25-D can lead to low levels of other hormones.+The increase in 1,25-D introduces a new problem entirely. When 1,25-D reaches higher and higher levels, it begins to interfere with important activities of other nuclear receptors. While 1,25-D is the activating hormone for the VDR, at high enough levels it binds to and inactivates other receptors. Like the VDR, these receptors have a role in innate immune function, but they also transcribe genes that lead to production of hormones of their own such as thyroid hormones and the sex hormones. This is why high levels of 1,25-D can lead to low levels of other hormones.
  
  
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-{{tag>Simple_Explanations Starting_the_Marshall_Protocol}}+{{tag>MP Simple_Explanations Starting_the_Marshall_Protocol}}
  
  
home/mp/stages.txt · Last modified: 09.14.2022 by 127.0.0.1
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