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home:mp:stages [07.18.2015] – [Stage 2: Unhealthy VDR, pathogens downregulate immune activity] joyfulhome:mp:stages [12.14.2018] – [Stage 1: Healthy Vitamin D Receptor (VDR), low pathogen load] sallieq
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-=====Stage 1: Healthy Vitamin D Receptor (VDR), low pathogen load =====+=====  Prior to immune dysfunction =====
  
 In a healthy human, the body can carefully regulate activity of the VDR, which it does by controlling the concentrations of two key forms of vitamin D: 25-D and 1,25-D. Both molecules are attracted to the Receptor and bind to it for hours at a time, after which they drop off. The essential difference between the key molecules is that when 1,25-D docks to the VDR, it turns the Receptor on; when 25-D docks to the VDR, it is turned off. When it becomes necessary to turn on the VDR, the body increases production of 1,25-D. Conversely, when an active VDR is no longer necessary, the body converts 1,25-D into 25-D. In healthy humans, this control mechanism works well. For example, in the event a pathogen is noticed, the body increases production of 1,25-D, which in turn increases activity of the VDR. In a healthy human, the body can carefully regulate activity of the VDR, which it does by controlling the concentrations of two key forms of vitamin D: 25-D and 1,25-D. Both molecules are attracted to the Receptor and bind to it for hours at a time, after which they drop off. The essential difference between the key molecules is that when 1,25-D docks to the VDR, it turns the Receptor on; when 25-D docks to the VDR, it is turned off. When it becomes necessary to turn on the VDR, the body increases production of 1,25-D. Conversely, when an active VDR is no longer necessary, the body converts 1,25-D into 25-D. In healthy humans, this control mechanism works well. For example, in the event a pathogen is noticed, the body increases production of 1,25-D, which in turn increases activity of the VDR.
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-{{tag>Simple_Explanations Starting_the_Marshall_Protocol}}+{{tag>MP Simple_Explanations Starting_the_Marshall_Protocol}}
  
  
home/mp/stages.txt · Last modified: 09.14.2022 by 127.0.0.1
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