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--- home:othertreatments:antifungals [03.06.2011] – external edit 127.0.0.1
+++ home:othertreatments:antifungals [01.15.2013] – [Types of antifungal agents] paulalbert
@@ Line 1: / Line 1: @@
 ====== Antifungal agents ======
-<relatedarticle> [[home:patients:assessing_literature:palliative|Palliative vs. curative treatments]] </article>
+<relatedarticles> [[home:diseases:co-infections|Co-infections]], [[home:patients:assessing_literature:palliative|Palliative vs. curative treatments]] </article>
@@ Line 25: / Line 25: @@
   * itraconazole (Sporonox)
   * ketoconazole (Nizoral)
+  * nimesulide (Aulin, Mesulid, Nimed) - may promote bleeding
   * nystatin
   * terfinabine (Lamisil)
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 ===== Notes and comments =====
-EDIT
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     * http://www.marshallprotocol.com/view_topic.php?id=3139&forum_id=37&jump_to=34393#p34393 s226
     *
-    *
+<blockquote>I did a quick pubmed seach and found two useful articles that indicate natamycin’s action may be “to disturb ergosterol-dependent protein functions” and that  “natamycin acts via a novel mode of action and blocks fungal growth by binding specifically to ergosterol” rather than acting on the fungi cell membrane.
+. Natamycin Inhibits Vacuole Fusion at the Priming Phase via a Specific Interaction with Ergoste http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876427/
+. Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane. http://www.jbc.org/content/283/10/6393.long
+While a search in wikapedia states under natamycin saftety that, “Natamycin lacks acute toxicity" it then goes on to state that “In humans, a dose of 500 mg/kg/day repeated over multiple days caused nausea, vomiting, and diarrhea.”
+</blockquote>
 ===== References =====

home/othertreatments/antifungals.txt · Last modified: 09.14.2022 by 127.0.0.1