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home:othertreatments:antifungals [08.02.2017] – [Patients experiences] + 2 quotes from bobi's thread sallieqhome:othertreatments:antifungals [09.14.2022] (current) – external edit 127.0.0.1
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 Antifungal agents such as fluconazole (Diflucan) are sometimes prescribed to treat fungal infections, of which //Candida// is one kind. While some patients have reported feeling better after taking antifungal agents, antifungals interfere with immune function.  Antifungal agents such as fluconazole (Diflucan) are sometimes prescribed to treat fungal infections, of which //Candida// is one kind. While some patients have reported feeling better after taking antifungal agents, antifungals interfere with immune function. 
  
-The antifungals directly inhibit the enzyme CYP27B1, which is needed for the mitichondria in the macrophages to convert 25-D to 1,25-D.(({{pubmed>long:12520539}})) With an artificially depressed rate of generating 1,25-D, patients taking antifungals tend to feel better for a period and then relapse worse than before.+The antifungals directly inhibit the enzyme CYP27B1, which is needed for the mitichondria in the macrophages to convert 25-D to 1,25-D.(({{pmid>long:12520539}})) With an artificially depressed rate of generating 1,25-D, patients taking antifungals tend to feel better for a period and then relapse worse than before.
  
 By increasing levels of 25-D and therefore inhibiting immunopathology, long-term use of antifungal drugs may delay progress on the Marshall Protocol (MP). By increasing levels of 25-D and therefore inhibiting immunopathology, long-term use of antifungal drugs may delay progress on the Marshall Protocol (MP).
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 Patient symptom scores were a poor predictor of yeast infections based on yeast culture results. ... Self-reported symptoms are not reliable for diagnosis. Patient symptom scores were a poor predictor of yeast infections based on yeast culture results. ... Self-reported symptoms are not reliable for diagnosis.
  
-//**Susan Hoffstetter** et al.// (({{pubmed>long:18664056}})) </blockquote> +//**Susan Hoffstetter** et al.// (({{pmid>long:18664056}})) </blockquote> 
  
  
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 +<nodisp>
 ===== Notes and comments ===== ===== Notes and comments =====
  
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 From: Dr. Greg Blaney From: Dr. Greg Blaney
 Date: 2010-07-04 14:39:15 Date: 2010-07-04 14:39:15
-Reply: http://www.marshallprotocol.com/reply.php?topic_id=13184+Reply: https://www.marshallprotocol.com/reply.php?topic_id=13184
  
 <blockquote>If candida is suspected, I usually treat prior to starting MP. This is often helpful also as gives a mild herx reaction and can prepare them for MP herx. Occasionally, I have used nystatin with patients on Benicar. These are usually patients who have had high dose antibiotics for Lyme disease in the past. This is very rare though. <blockquote>If candida is suspected, I usually treat prior to starting MP. This is often helpful also as gives a mild herx reaction and can prepare them for MP herx. Occasionally, I have used nystatin with patients on Benicar. These are usually patients who have had high dose antibiotics for Lyme disease in the past. This is very rare though.
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   * Legacy content   * Legacy content
-    * http://www.marshallprotocol.com/view_topic.php?id=3139&forum_id=37&jump_to=34393#p34393 s226+    * https://www.marshallprotocol.com/view_topic.php?id=3139&forum_id=37&jump_to=34393#p34393 s226
     *      * 
  
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-1. Natamycin Inhibits Vacuole Fusion at the Priming Phase via a Specific Interaction with Ergoste http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876427/+1. Natamycin Inhibits Vacuole Fusion at the Priming Phase via a Specific Interaction with Ergoste https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876427/
  
  
  
-2. Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane. http://www.jbc.org/content/283/10/6393.long+2. Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane. https://www.jbc.org/content/283/10/6393.long
  
  
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 While a search in wikapedia states under natamycin saftety that, “Natamycin lacks acute toxicity" it then goes on to state that “In humans, a dose of 500 mg/kg/day repeated over multiple days caused nausea, vomiting, and diarrhea.” While a search in wikapedia states under natamycin saftety that, “Natamycin lacks acute toxicity" it then goes on to state that “In humans, a dose of 500 mg/kg/day repeated over multiple days caused nausea, vomiting, and diarrhea.”
 </blockquote> </blockquote>
-===== References =====+===== References =====</nodisp> 
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