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--- home:othertreatments:antioxidants [05.02.2011] – external edit 127.0.0.1
+++ home:othertreatments:antioxidants [07.03.2011] – [Interference with apoptosis] paulalbert
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-===== Unknown molecular actions =====
+===== Problematic and unknown molecular actions =====
-Antioxidants have widespread effects throughout the body, many of which are not well documented or quantified.
+Antioxidants have widespread effects throughout the body, a number of which are not well documented or quantified. Researchers are beginning to suspect that the body may actually need free radicals, which help kill cancerous cells, ensure optimal immune function, and regulate blood sugar.
-<blockquote>
+It seems safe to say that one's body has all the necessary requirements to carry on these functions in the presence of a balanced diet.  Placing additional chemistry into the mix is unwise and could be a deterrent to the positive outcome a patient is striving for on the MP.
-[Antioxidants] can possess capabilities to ineffectuate some of the chemistry going on to dismantle the causation of your disease: the Th1 pathogens.
+==== Interference with apoptosis ====
+Apoptosis, or regulated cell suicide, eliminates unwanted and damaged cells, including precancerous and cancerous cells. Reactive oxygen species (ROS) are chemically-reactive molecules containing oxygen, which act to neutralize antioxidants, regulate apoptosis(({{pubmed>long:11256882}})). In their 2000 study, Salganki //et al.// reasoned that since ROS act as essential apoptotic mediators, increasing the ROS level might enhance apoptosis and thereby slow down tumor growth.(({{pubmed>long:10783311}})) Provocatively, that team showed that tumor growth was inhibited in mice fed an antioxidant-depleted diet while an antioxidant-rich diet had no impact on tumor growth. This work, while preliminary, offers one mechanism how megadoses of antioxidants are not protective against cancer and may actually exacerbate unchecked cell growth.
-Your body has all the necessary requirements to carry on these functions in the presence of a balanced diet.  Placing additional chemistry into the mix is unwise and could be a deterrent to the positive outcome you are striving for on the MP.
-//**Vez**, MarshallProtocol.com// </blockquote>
 ===== Evidence against supplementation =====
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 //**Lisa Melton**, [[http://www.newscientist.com/article/mg19125631.500-the-antioxidant-myth-a-medical-fairy-tale.html|New Scientist]]// </blockquote>
+Researchers at Memorial Sloan-Kettering Cancer Center studied the effects of vitamin C on cancer cells.(({{pubmed>long:18829561}})) As it turns out, the vitamin seems to protect not just healthy cells, but cancer cells, too. “The use of vitamin C supplements could have the potential to reduce the ability of patients to respond to therapy,” said Dr. Mark Heaney, an associate attending physician at the cancer center.
+Dr. Heaney and his colleagues tested five different chemotherapy drugs on cancer cells in the laboratory. Some of the cells were first treated with vitamin C. In each case and in dose-dependent fashion, chemotherapy did not work as well if cells had been exposed to vitamin C. The chemotherapy agents killed 30 to 70 percent fewer cancer cells when the cells were treated with the vitamin.
+A second set of experiments implanted cancer cells in mice. They found that the tumors grew more rapidly in mice that were given cancer cells pretreated with vitamin C. The researchers found that just like healthy cells, cancer cells also benefit from vitamin C. The vitamin appeared to repair a cancer cell’s damaged mitochondria, the energy center of cells. When the mitochondria is injured, it sends signals that force the cell to die, but vitamin C interrupts that process.
+“Vitamin C appears to protect the mitochondria from extensive damage, thus saving the cell,” Dr. Heaney said. “And whether directly or not, all anticancer drugs work to disrupt the mitochondria to push cell death.”
 ==== Selenium ====
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+===== Read more =====
+* [[http://well.blogs.nytimes.com/2008/10/01/vitamin-c-may-interfere-with-cancer-treatment/|Vitamin C May Interfere With Cancer Treatment]]

home/othertreatments/antioxidants.txt · Last modified: 09.14.2022 by 127.0.0.1