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--- home:othertreatments:antioxidants [07.03.2011] – paulalbert
+++ home:othertreatments:antioxidants [07.03.2011] – [Interference with apoptosis] paulalbert
@@ Line 20: / Line 20: @@
 ==== Interference with apoptosis ====
-Apoptosis, or regulated cell suicide, eliminates unwanted and damaged cells, including precancerous and cancerous cells. Reactive oxygen species are chemically-reactive molecules containing oxygen that act to neutralize antioxidants.
+Apoptosis, or regulated cell suicide, eliminates unwanted and damaged cells, including precancerous and cancerous cells. Reactive oxygen species (ROS) are chemically-reactive molecules containing oxygen that act to neutralize antioxidants. In their 2000 study, Salganki //et al.// reasoned that since ROS act as essential apoptotic mediators, increasing the ROS level might enhance apoptosis and thereby slow down tumor growth.(({{pubmed>long:10783311}})) Provocatively, that team showed that tumor growth was inhibited in mice fed an antioxidant-depleted diet while an antioxidant-rich diet had no impact on tumor growth. This work, while preliminary, offers one mechanism how megadoses of antioxidants are not protective against cancer and may actually exacerbate it.

home/othertreatments/antioxidants.txt · Last modified: 09.14.2022 by 127.0.0.1