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home:othertreatments:antioxidants [07.03.2011]
paulalbert [Interference with apoptosis]
home:othertreatments:antioxidants [01.03.2012] (current)
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 ==== Interference with apoptosis ==== ==== Interference with apoptosis ====
  
-Apoptosis, or regulated cell suicide, eliminates unwanted and damaged cells, including precancerous and cancerous cells. Reactive oxygen species (ROS) are chemically-reactive molecules containing oxygen ​that act to neutralize antioxidants. In their 2000 study, Salganki //et al.// reasoned that since ROS act as essential apoptotic mediators, increasing the ROS level might enhance apoptosis and thereby slow down tumor growth.(({{pubmed>​long:​10783311}})) Provocatively,​ that team showed that tumor growth was inhibited in mice fed an antioxidant-depleted diet while an antioxidant-rich diet had no impact on tumor growth. This work, while preliminary,​ offers one mechanism how megadoses of antioxidants are not protective against cancer and may actually exacerbate ​it. +Apoptosis, or regulated cell suicide, eliminates unwanted and damaged cells, including precancerous and cancerous cells. Reactive oxygen species (ROS) are chemically-reactive molecules containing oxygen, which act to neutralize antioxidants, regulate apoptosis(({{pubmed>​long:​11256882}})). In their 2000 study, Salganki //et al.// reasoned that since ROS act as essential apoptotic mediators, increasing the ROS level might enhance apoptosis and thereby slow down tumor growth.(({{pubmed>​long:​10783311}})) Provocatively,​ that team showed that tumor growth was inhibited in mice fed an antioxidant-depleted diet while an antioxidant-rich diet had no impact on tumor growth. This work, while preliminary,​ offers one mechanism how megadoses of antioxidants are not protective against cancer and may actually exacerbate ​unchecked cell growth.
  
  
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 {{tag>​non-MP_therapies}} {{tag>​non-MP_therapies}}
 ===== Notes and comments ===== ===== Notes and comments =====
-EDIT+
  
 "It may well be that the only one benefiting from supplements is the one making the profits."​ "It may well be that the only one benefiting from supplements is the one making the profits."​
home/othertreatments/antioxidants.txt · Last modified: 01.03.2012 (external edit)
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