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A variety of medications including the bisphosphonates have been touted to conserve or increase bone mass. These drugs have a number of side effects and are known or suspected to interfere with proper immune function. | A variety of medications including the bisphosphonates have been touted to conserve or increase bone mass. These drugs have a number of side effects and are known or suspected to interfere with proper immune function. | ||
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===== Bisphosphonates ===== | ===== Bisphosphonates ===== | ||
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* atrial fibrillation – Numerous studies have shown that the frequency of atrial fibrillation increases with increasing age in both men and women. Data from the Framingham Heart Study showed a greater biennial incidence of AF with increasing age, with the odds ratio rising by a factor of 2.2 for every additional 10 years of age.(({{pubmed> | * atrial fibrillation – Numerous studies have shown that the frequency of atrial fibrillation increases with increasing age in both men and women. Data from the Framingham Heart Study showed a greater biennial incidence of AF with increasing age, with the odds ratio rising by a factor of 2.2 for every additional 10 years of age.(({{pubmed> | ||
* calcium deposition in the soft tissues(({{pubmed> | * calcium deposition in the soft tissues(({{pubmed> | ||
+ | * osteonecrosis of the jaw, i.e. bone death | ||
* reduced organ function, e.g. renal dysfunction or failure | * reduced organ function, e.g. renal dysfunction or failure | ||
- | * osteonecrosis of the jaw, i.e. bone death | ||
Those patients with elevated 1,25-D – which is [[home: | Those patients with elevated 1,25-D – which is [[home: |