This shows you the differences between two versions of the page.
Both sides previous revisionPrevious revisionNext revision | Previous revisionLast revisionBoth sides next revision | ||
home:othertreatments:boneagents [01.08.2010] – paulalbert | home:othertreatments:boneagents [10.25.2010] – paulalbert | ||
---|---|---|---|
Line 3: | Line 3: | ||
- | <html>< | + | <relatedarticle> [[home: |
A variety of medications including the bisphosphonates have been touted to conserve or increase bone mass. These drugs have a number of side effects and are known or suspected to interfere with proper immune function. | A variety of medications including the bisphosphonates have been touted to conserve or increase bone mass. These drugs have a number of side effects and are known or suspected to interfere with proper immune function. | ||
Line 10: | Line 10: | ||
Bone has constant turnover, and is kept in balance (homeostasis) by osteoblasts creating bone and osteoclasts digesting bone. Bisphosphonates inhibit the digesting of bone by osteoclasts. | Bone has constant turnover, and is kept in balance (homeostasis) by osteoblasts creating bone and osteoclasts digesting bone. Bisphosphonates inhibit the digesting of bone by osteoclasts. | ||
- | Bisphosphonates have a variety of side effects: | + | The bisphosphonate has a variety of side effects: |
* chronic musculoskeletal pain(({{pubmed> | * chronic musculoskeletal pain(({{pubmed> | ||
* atrial fibrillation – Numerous studies have shown that the frequency of atrial fibrillation increases with increasing age in both men and women. Data from the Framingham Heart Study showed a greater biennial incidence of AF with increasing age, with the odds ratio rising by a factor of 2.2 for every additional 10 years of age.(({{pubmed> | * atrial fibrillation – Numerous studies have shown that the frequency of atrial fibrillation increases with increasing age in both men and women. Data from the Framingham Heart Study showed a greater biennial incidence of AF with increasing age, with the odds ratio rising by a factor of 2.2 for every additional 10 years of age.(({{pubmed> | ||
Line 20: | Line 20: | ||
All these meds have some effect on the immune or endocrine system and are, therefore, to be avoided. | All these meds have some effect on the immune or endocrine system and are, therefore, to be avoided. | ||
+ | |||
==== Types of bisphopshonates ==== | ==== Types of bisphopshonates ==== | ||
Line 44: | Line 45: | ||
EDIT | EDIT | ||
+ | FDA Alert - Oral Bisphosphonates: | ||
===== References ===== | ===== References ===== |