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home:othertreatments:epo [09.14.2022] (current) – external edit 127.0.0.1
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 +~~NOTOC~~
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 +====== Erythropoiesis-stimulating agents (EPO) ======
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 +Erythropoietin, or its alternatives erythropoetin or erithropoyetin or EPO, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. A 2011 study found that in mice infected with //Salmonella//, EPO treatment was associated with reduced survival and impaired ability to clear the pathogen, neutralization of EPO production in the body promoted //Salmonella// elimination. This suggests that EPO reduces the ability of the immune system to fight off a systemic infection with intracellular bacteria such as //Salmonella//.((Manfred Nairz, Andrea Schroll, Alexander R. Moschen, Thomas Sonnweber, Milan Theurl, Igor Theurl, Nicole Taub, Christina Jamnig, Daniela Neurauter, Lukas A. Huber, Herbert Tilg, Patrizia L. Moser, and Günter Weiss. Erythropoietin Contrastingly Affects Bacterial Infection and Experimental Colitis by Inhibiting Nuclear Factor-κB-Inducible Immune Pathways. Immunity, 2011; DOI: 10.1016/j.immuni.2011.01.002.))
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 +Because EPO is highly immunosuppressive and exacerbates intra-cellular infection, its use is not recommended.
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 +
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 +===== Read more =====
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 +  * [[https://www.sciencedaily.com/releases/2011/01/110120151641.htm|Red Blood Cell Hormone Modulates the Immune System]]
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 +<nodisp>
 +===== Notes and comments =====
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 +
 +===== References =====</nodisp>
  
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