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home:othertreatments:herbs_and_spices [05.26.2014] – [Milk thistle] jjhome:othertreatments:herbs_and_spices [11.21.2017] – [Grapefruit seed extract] + diet & drug metabolism sallieq
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 ==== Curcumin, tumeric, curry and mustard ==== ==== Curcumin, tumeric, curry and mustard ====
  
-MP patients should avoid significant use of curcumin as well as its derivatives. A 2010 by Choi //et al.// showed that curcumin decreases androgen receptor expression in a dose-dependent manner.(({{pubmed>long:20680030}})) According to a [[http://tinyurl.com/nflgz|2006 Food Technology article]]+MP patients should avoid significant use of curcumin as well as its derivatives. A 2010 by Choi //et al.// showed that curcumin decreases androgen receptor expression in a dose-dependent manner.(({{pubmed>long:20680030}})) According to a 2006 Food Technology article: 
  
 <blockquote> <blockquote>
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 Grapefruit seed extract is a powerful, broad-spectrum antimicrobial and anti-viral agent and is therefore contraindicated. Grapefruit seed extract is a powerful, broad-spectrum antimicrobial and anti-viral agent and is therefore contraindicated.
 +
 +Grapefruit juice inhibits CYP3A4 - mediated drug metabolism [[http://www.globalrph.com/gfruit.htm|drug-grapefruit interactions]]
 +This interaction can lead to increases in bioavailability and corresponding increases in serum drug levels. 
 +
 +see also Evans, Allan M.  in  Therapeutic Drug Monitoring: February 2000 - Volume 22 - Issue 1 - pp 131-136  
 + //Influence of Dietary Components on the Gastrointestinal Metabolism and Transport of Drugs//
  
  
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 For quick relief (especially when the digestive system is not working well), liquid milk thistle drops, which are usually available from a local health food store, may be helpful. Drops can be used in addition to the capsules, if needed. For quick relief (especially when the digestive system is not working well), liquid milk thistle drops, which are usually available from a local health food store, may be helpful. Drops can be used in addition to the capsules, if needed.
  
-The  Natural Medicines Comprehensive Database describes [[http://naturaldatabaseconsumer.therapeuticresearch.com/nd/Search.aspx?cs=KAISER&s=NDC&pt=100&sh=1&id=138#safety]] that anyone considering its use may want to review. +The  Natural Medicines Comprehensive Database describes [[http://naturaldatabaseconsumer.therapeuticresearch.com/nd/Search.aspx?cs=KAISER&s=NDC&pt=100&sh=1&id=138#safety|safety and drug interactions]] that anyone considering its use may want to review. 
 ==== Olive leaf extract ==== ==== Olive leaf extract ====
  
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 ===== Notes and comments ===== ===== Notes and comments =====
 +broke [[http://tinyurl.com/nflgz|2006 Food Technology article]]
  
  
home/othertreatments/herbs_and_spices.txt · Last modified: 09.14.2022 by 127.0.0.1
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