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home:othertreatments:herbs_and_spices [05.26.2014] – [Milk thistle] jj | home:othertreatments:herbs_and_spices [11.21.2017] – [Grapefruit seed extract] sallieq | ||
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==== Curcumin, tumeric, curry and mustard ==== | ==== Curcumin, tumeric, curry and mustard ==== | ||
- | MP patients should avoid significant use of curcumin as well as its derivatives. A 2010 by Choi //et al.// showed that curcumin decreases androgen receptor expression in a dose-dependent manner.(({{pubmed> | + | MP patients should avoid significant use of curcumin as well as its derivatives. A 2010 by Choi //et al.// showed that curcumin decreases androgen receptor expression in a dose-dependent manner.(({{pubmed> |
< | < | ||
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Grapefruit seed extract is a powerful, broad-spectrum antimicrobial and anti-viral agent and is therefore contraindicated. | Grapefruit seed extract is a powerful, broad-spectrum antimicrobial and anti-viral agent and is therefore contraindicated. | ||
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+ | Grapefruit juice inhibits CYP3A4 - mediated drug metabolism [[http:// | ||
+ | This interaction can lead to increases in bioavailability and corresponding increases in serum drug levels. | ||
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For quick relief (especially when the digestive system is not working well), liquid milk thistle drops, which are usually available from a local health food store, may be helpful. Drops can be used in addition to the capsules, if needed. | For quick relief (especially when the digestive system is not working well), liquid milk thistle drops, which are usually available from a local health food store, may be helpful. Drops can be used in addition to the capsules, if needed. | ||
- | The Natural Medicines Comprehensive Database describes [[http:// | + | The Natural Medicines Comprehensive Database describes [[http:// |
==== Olive leaf extract ==== | ==== Olive leaf extract ==== | ||
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The calculated affinity is high, at Ki = 54 nanomolar, about the same as the less effective ARBs and statins. As a result, only a very small amount of carnosic acid is needed to produce a negative effect. | The calculated affinity is high, at Ki = 54 nanomolar, about the same as the less effective ARBs and statins. As a result, only a very small amount of carnosic acid is needed to produce a negative effect. | ||
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+ | ==== EFA and Unsaturated oils ==== | ||
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===== Notes and comments ===== | ===== Notes and comments ===== | ||
+ | broke [[http:// | ||