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home:othertreatments:herbs_and_spices [11.21.2017] – [Rosemary and sage] + oils in common use sallieqhome:othertreatments:herbs_and_spices [12.15.2018] – [Curcumin, tumeric, curry and mustard] + cancer research sallieq
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 ==== Curcumin, tumeric, curry and mustard ==== ==== Curcumin, tumeric, curry and mustard ====
  
-MP patients should avoid significant use of curcumin as well as its derivatives. A 2010 by Choi //et al.// showed that curcumin decreases androgen receptor expression in a dose-dependent manner.(({{pubmed>long:20680030}})) According to a 2006 Food Technology article: +MP patients aree advised to avoid significant use of curcumin as well as its derivatives. A 2010 by Choi //et al.// showed that curcumin decreases androgen receptor expression in a dose-dependent manner.(({{pubmed>long:20680030}})) According to a 2006 Food Technology article: 
  
 <blockquote> <blockquote>
 Twelve scientific, peer-reviewed publications since 1999 suggest that curcumin, the major yellow pigment in tumeric, curry and mustard, may potentiate apoptosis or inhibit growth of selected cancer cells or function as a COX-2 inhibitor in several in-vitro and animal models.</blockquote> Twelve scientific, peer-reviewed publications since 1999 suggest that curcumin, the major yellow pigment in tumeric, curry and mustard, may potentiate apoptosis or inhibit growth of selected cancer cells or function as a COX-2 inhibitor in several in-vitro and animal models.</blockquote>
 +
 +Cucurmin certainly appears to impact the immune system, and therefore may increasse IP in an unpredictable way.  (({{pubmed>long:27874279}}))  (({{pubmed>long:21461234}}))
  
  
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 Grapefruit juice inhibits CYP3A4 - mediated drug metabolism [[http://www.globalrph.com/gfruit.htm|drug-grapefruit interactions]] Grapefruit juice inhibits CYP3A4 - mediated drug metabolism [[http://www.globalrph.com/gfruit.htm|drug-grapefruit interactions]]
-This interaction can lead to increases in bioavailability and corresponding increases in serum drug levels. +This interaction can lead to increases in bioavailability and corresponding increases in serum drug levels.  (({{pubmed>long:10688276}}))
  
-see also Evans, Allan M.  in  Therapeutic Drug Monitoring: February 2000 - Volume 22 - Issue 1 - pp 131-136   
- //Influence of Dietary Components on the Gastrointestinal Metabolism and Transport of Drugs// 
  
  
home/othertreatments/herbs_and_spices.txt · Last modified: 09.14.2022 by 127.0.0.1
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