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home:othertreatments:pain_medication [02.06.2019] – [Pain medications and muscle relaxants] sallieqhome:othertreatments:pain_medication [02.23.2019] – [Types of pain medications] sallieq
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 In conjunction with their physician or a pain management specialist, patients may want to experiment with different pain killers to see if any of them seem to lower not just pain but other disease symptoms. If they feel a particular pain medication is lowering immunopathology they are able to tolerate, they may want to ask their physician to change to a medication that does not elicit such an effect. In conjunction with their physician or a pain management specialist, patients may want to experiment with different pain killers to see if any of them seem to lower not just pain but other disease symptoms. If they feel a particular pain medication is lowering immunopathology they are able to tolerate, they may want to ask their physician to change to a medication that does not elicit such an effect.
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 +<blockquote>slowly I determined that caffeine, stress, and heat were triggers for all of my [[https://www.diagnosisms.com/2011/04/29/what-is-the-ms-hug/|muscle spasms]] ..//Internet article by MS sufferer//</blockquote> 
 ===== Types of pain medications ===== ===== Types of pain medications =====
  
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   * **morphine** – avoid if possible - shown to be immunosuppressive in a study(({{pubmed>long:9208156}}))   * **morphine** – avoid if possible - shown to be immunosuppressive in a study(({{pubmed>long:9208156}}))
   * **naltrexone** – an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. Naltrexone would certainly appear to affect the ability of the MP to return the human immune system to full function again. Lymphocytes express opioid receptors, probably for a good reason. Even though that reason is not fully understood, it is not a good idea to block those opioid receptors (with naltrexone) if one expects to be able to return your immune system to normal.   * **naltrexone** – an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. Naltrexone would certainly appear to affect the ability of the MP to return the human immune system to full function again. Lymphocytes express opioid receptors, probably for a good reason. Even though that reason is not fully understood, it is not a good idea to block those opioid receptors (with naltrexone) if one expects to be able to return your immune system to normal.
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 +Ultra-low dose naltrexone enhances cannabinoid-induced antinociception.  (({{pubmed>long:16286810}}))
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 +Surprisingly, the analgesic effects of opioids are enhanced by ultra-low doses (nanomolar to picomolar) of the opioid antagonist, naltrexone.
  
 <blockquote>Low dose naltrexone (LDN) is palliative. It doesn't help the innate immune system in any significant way. If it were helping the immune system to kill the microbiota then your immunopathology would increase, not decrease. However, I have looked into whether it is likely to stop healing, and it does not seem to interfere with the known actions of Olmesartan on the VDR. So it seems a "safe" palliative. There was a [[http://www.curemyth1.org/view_topic.php?id=3589&forum_id=2&jump_to=31773|thread on CureMyTh1.org]] where these issues were briefly discussed. <blockquote>Low dose naltrexone (LDN) is palliative. It doesn't help the innate immune system in any significant way. If it were helping the immune system to kill the microbiota then your immunopathology would increase, not decrease. However, I have looked into whether it is likely to stop healing, and it does not seem to interfere with the known actions of Olmesartan on the VDR. So it seems a "safe" palliative. There was a [[http://www.curemyth1.org/view_topic.php?id=3589&forum_id=2&jump_to=31773|thread on CureMyTh1.org]] where these issues were briefly discussed.
home/othertreatments/pain_medication.txt · Last modified: 09.14.2022 by 127.0.0.1
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