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home:othertreatments:sunshine [09.20.2011] – [Notes and comments] paulalbert | home:othertreatments:sunshine [03.29.2017] – [Read more] sallieq | ||
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+ | Phototherapy suppresses immunity which can lead to the progression of other infections such as human papilloma virus (HPV). A 2010 study used a nested polymerase chain reaction, to analyze skin biopsies taken a from 20 psoriasis patients under phototherapy (UVB) and 20 untreated psoriatic patients. The authors were able to detect viruses in 60% of the treatment but in none of the controls.(({{pubmed> | ||
A 2011 study by Damian //et al.// concluded that exposure to sunlight even at suberythemal levels – sunlight which doesn' | A 2011 study by Damian //et al.// concluded that exposure to sunlight even at suberythemal levels – sunlight which doesn' | ||
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+ | Certain support for this study comes from a 2011 Australian paper that found that 8 week old mice given a single exposure of ultraviolet radiation had suppressed immunity.(({{pubmed> | ||
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===== By providing temporary symptom relief, tanning may be addictive ===== | ===== By providing temporary symptom relief, tanning may be addictive ===== | ||
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===== Notes and comments ===== | ===== Notes and comments ===== | ||
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+ | The mechanisms and consequences of ultraviolet-induced immunosuppression in the skin and eye. | ||
+ | Norval M. | ||
+ | Source | ||
+ | From Biomedical Sciences, University of Edinburgh, Scotland, United Kingdom. | ||
+ | Abstract | ||
+ | Ultraviolet radiation (UVR) of the skin results in immune suppression to antigens encountered shortly after the exposure. The pathways leading to the downregulation in immunity are complex, initiated by chromophores located at the surface of the skin and ending with the generation of immunosuppressive mediators and regulatory cells. Ultraviolet-induced immunosuppression can be considered not only as beneficial, such as in preventing chronic inflammatory responses and allergic and automimmune reactions, but it can also be detrimental, | ||
+ | PMID: 21709488 | ||
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+ | Little information is available currently as most epidemiological surveys that have monitored immune responses to vaccines do not consider solar UVR or the sun exposure of individuals, | ||
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+ | 62. Colditz GA, Brewer TF, Berkey CS, et al. Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature. JAMA 1994; | ||
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+ | 63. John TJ, Jayabal P. Oral polio vaccination of children in the tropics. I. The poor seroconversion rates and the absence of viral interference. Am J Epidemiol 1972; | ||
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+ | 64. Linder N, Abudi Y, Abdulla W, et al. Effect of season of inoculation on immune response to rubella vaccine in children. J Trop Pediatr [published online ahead of print November 4, 2009]. doi: | ||
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