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home:othertreatments:sunshine [06.30.2019] – [Sunlight can be immunosuppressive] sallieqhome:othertreatments:sunshine [09.14.2022] (current) – external edit 127.0.0.1
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 Contrary to popular belief, epidemiological research points to an //increase// in suicide across countries during the beginning of the summer months when people tend to get more light exposure. Contrary to popular belief, epidemiological research points to an //increase// in suicide across countries during the beginning of the summer months when people tend to get more light exposure.
  
-Light exposure does nothing to resolve underlying disease state and can actually delay progress for Marshall Protocol (MP) patients. Certainly prolonged light exposure has been shown to increase skin melanoma – the World Health Organization now categorizes tanning beds under the highest cancer risk category.(({{pubmed>long:19655431}})) +Light exposure does nothing to resolve underlying disease state and can actually delay progress for Marshall Protocol (MP) patients. Certainly prolonged light exposure has been shown to increase skin melanoma – the World Health Organization now categorizes tanning beds under the highest cancer risk category.(({{pmid>long:19655431}})) 
  
 MP patients who have completed the treatment have been able to attest to the fact that sunshine is not necessary for good health or happiness. MP patients who have completed the treatment have been able to attest to the fact that sunshine is not necessary for good health or happiness.
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 ===== Sunshine and suicide ===== ===== Sunshine and suicide =====
  
-In spite of a widespread belief that the peak occurs in late autumn and early winter,(({{pubmed>long:17688099}})) a positive correlation between sunlight and suicide has been demonstrated by several researchers.+In spite of a widespread belief that the peak occurs in late autumn and early winter,(({{pmid>long:17688099}})) a positive correlation between sunlight and suicide has been demonstrated by several researchers.
  
 <blockquote>We found a remarkably consistent pattern of seasonality with peak incidence around June in the northern hemisphere and December in the southern hemisphere. Moreover, there was a positive association between the seasonal amplitude of suicide (measured by relative risk) and total sunshine in the corresponding country. These findings indicate that sunshine may have a triggering effect on suicide.... <blockquote>We found a remarkably consistent pattern of seasonality with peak incidence around June in the northern hemisphere and December in the southern hemisphere. Moreover, there was a positive association between the seasonal amplitude of suicide (measured by relative risk) and total sunshine in the corresponding country. These findings indicate that sunshine may have a triggering effect on suicide....
  
-//**Eleni Petridou,** et al// (({{pubmed>long:11805594}}))</blockquote>+//**Eleni Petridou,** et al// (({{pmid>long:11805594}}))</blockquote>
  
 Petridou's work is striking, because it identifies an effect for all 20 countries studied: Petridou's work is striking, because it identifies an effect for all 20 countries studied:
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 Increased summer incidence of suicide has also been identified in other countries including Increased summer incidence of suicide has also been identified in other countries including
-Finland,(({{pubmed>long:9718233}}))  +Finland,(({{pmid>long:9718233}}))  
-Norway,(({{pubmed>long:12103450}}))  +Norway,(({{pmid>long:12103450}}))  
-Belgium,(({{pubmed>long:8352350}}))  +Belgium,(({{pmid>long:8352350}}))  
-France,(({{pubmed>long:2960714}}))  +France,(({{pmid>long:2960714}}))  
-Italy,(({{pubmed>long:9241572}})) +Italy,(({{pmid>long:9241572}})) 
- Japan,(({{pubmed>long:15575348}})) + Japan,(({{pmid>long:15575348}})) 
-USA,(({{pubmed>long:2326139}})) +USA,(({{pmid>long:2326139}})) 
-Lithuania,(({{pubmed>long:16504069}}))  +Lithuania,(({{pmid>long:16504069}}))  
-Switzerland,(({{pubmed>long:16234425}})) +Switzerland,(({{pmid>long:16234425}})) 
-Chile,(({{pubmed>long:10030056}})) and +Chile,(({{pmid>long:10030056}})) and 
-South Africa.(({{pubmed>long:9061800}}))+South Africa.(({{pmid>long:9061800}}))
  
 In many, if not all, of these studies the increased incidence of suicide was shown to be independent of an increase in homicide. In many, if not all, of these studies the increased incidence of suicide was shown to be independent of an increase in homicide.
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-Phototherapy suppresses immunity which can lead to the progression of other infections such as human papilloma virus (HPV). A 2010 study used a nested polymerase chain reaction, to analyze skin biopsies taken a from 20 psoriasis patients under phototherapy (UVB) and 20 untreated psoriatic patients. The authors were able to detect viruses in 60% of the treatment but in none of the controls.(({{pubmed>long:20415738}})) +Phototherapy suppresses immunity which can lead to the progression of other infections such as human papilloma virus (HPV). A 2010 study used a nested polymerase chain reaction, to analyze skin biopsies taken a from 20 psoriasis patients under phototherapy (UVB) and 20 untreated psoriatic patients. The authors were able to detect viruses in 60% of the treatment but in none of the controls.(({{pmid>long:20415738}})) 
  
 1,25(OH)2D3 resulted in suppression of proinflammatory cytokine response in vitro 1,25(OH)2D3 resulted in suppression of proinflammatory cytokine response in vitro
-First, we carried out LPS and Pam3Cys stimulation on PBMC with the addition of 100 nM 1,25(OH)2D3. After 24 h, IL-6 secretion was reduced by 53% and 29% upon Pam3Cys and LPS stimulation, respectively, in the cells treated with 1,25(OH)2D3 (Fig. 1a). A significant drop in TNF-α production by 17% (Pam3Cys stimulation) and 35% (LPS stimulation) was also observed with 1,25(OH)2D3 at 24 h. Having demonstrated that 1,25(OH)2D3 had the capacity to modulated IL-6 and TNF-α response in vitro, and with the understanding that physiological vitamin D3 levels in the body may vary through the seasons, we validate these observations in vivo in a cohort of healthy volunteers.(({{pubmed>long:21323660}}))+First, we carried out LPS and Pam3Cys stimulation on PBMC with the addition of 100 nM 1,25(OH)2D3. After 24 h, IL-6 secretion was reduced by 53% and 29% upon Pam3Cys and LPS stimulation, respectively, in the cells treated with 1,25(OH)2D3 (Fig. 1a). A significant drop in TNF-α production by 17% (Pam3Cys stimulation) and 35% (LPS stimulation) was also observed with 1,25(OH)2D3 at 24 h. Having demonstrated that 1,25(OH)2D3 had the capacity to modulated IL-6 and TNF-α response in vitro, and with the understanding that physiological vitamin D3 levels in the body may vary through the seasons, we validate these observations in vivo in a cohort of healthy volunteers.(({{pmid>long:21323660}}))
  
-A 2011 study by Damian //et al.// concluded that exposure to sunlight even at suberythemal levels – sunlight which doesn't cause redness – is "profoundly immunosuppressive" in humans and that it is the immune-suppressive effects of sunlight that play a central role in skin carcinogenesis.(({{pubmed>long:21375518}}))+A 2011 study by Damian //et al.// concluded that exposure to sunlight even at suberythemal levels – sunlight which doesn't cause redness – is "profoundly immunosuppressive" in humans and that it is the immune-suppressive effects of sunlight that play a central role in skin carcinogenesis.(({{pmid>long:21375518}}))
  
-Certain support for this study comes from a 2011 Australian paper that found that 8 week old mice given a single exposure of ultraviolet radiation had suppressed immunity.(({{pubmed>long:21243005}}))+Certain support for this study comes from a 2011 Australian paper that found that 8 week old mice given a single exposure of ultraviolet radiation had suppressed immunity.(({{pmid>long:21243005}}))
  
-[[http://www.nejm.org/doi/full/10.1056/NEJMicm1104059|Unilateral Dermatoheliosis]]+[[https://www.nejm.org/doi/full/10.1056/NEJMicm1104059|Unilateral Dermatoheliosis]]
  
  
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 This phenomenon can be observed among different patient populations. This phenomenon can be observed among different patient populations.
  
-In recent years, researchers have begun to describe people addicted to tanning, at least according to criteria set out by the Diagnostic and Statistical Manual for substance-related disorders.(({{pubmed>long:19152511}})) One research team calls the addiction "UV light substance-related disorder."(({{pubmed>long:17257709}})) A 2010 study suggests individuals who have used indoor tanning facilities may meet criteria for addiction, and may also be more prone to anxiety symptoms and substance use.(({{pubmed>long:20404230}})) Among 229 study participants (students at a northeastern U.S. college) who had used indoor tanning facilities, the average number of visits during a given year was 23. A total of 90 (39.3 percent) met criteria for tanning addiction on one measure and 70 (30.6 percent) met criteria on the other measure. Students who did meet these criteria were more likely to report symptoms of anxiety and use of alcohol, marijuana and other substances than those who did not meet these criteria. +In recent years, researchers have begun to describe people addicted to tanning, at least according to criteria set out by the Diagnostic and Statistical Manual for substance-related disorders.(({{pmid>long:19152511}})) One research team calls the addiction "UV light substance-related disorder."(({{pmid>long:17257709}})) A 2010 study suggests individuals who have used indoor tanning facilities may meet criteria for addiction, and may also be more prone to anxiety symptoms and substance use.(({{pmid>long:20404230}})) Among 229 study participants (students at a northeastern U.S. college) who had used indoor tanning facilities, the average number of visits during a given year was 23. A total of 90 (39.3 percent) met criteria for tanning addiction on one measure and 70 (30.6 percent) met criteria on the other measure. Students who did meet these criteria were more likely to report symptoms of anxiety and use of alcohol, marijuana and other substances than those who did not meet these criteria. 
  
 <blockquote>If associations between affective factors and indoor tanning behavior are replicated, results suggest that treating an underlying mood disorder may be a necessary step in reducing skin cancer risk among those who frequently tan indoors. Researchers have hypothesized that those who tan regularly year round may require more intensive intervention efforts, such as motivational interviewing, relative to those who tan periodically in response to mood changes or special events. <blockquote>If associations between affective factors and indoor tanning behavior are replicated, results suggest that treating an underlying mood disorder may be a necessary step in reducing skin cancer risk among those who frequently tan indoors. Researchers have hypothesized that those who tan regularly year round may require more intensive intervention efforts, such as motivational interviewing, relative to those who tan periodically in response to mood changes or special events.
  
-//**Catherine E. Mosher, Ph.D. and Sharon Danoff-Burg, Ph.D.**//(({{pubmed>long:20404230}}))+//**Catherine E. Mosher, Ph.D. and Sharon Danoff-Burg, Ph.D.**//(({{pmid>long:20404230}}))
 </blockquote> </blockquote>
  
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-  * [[http://www.truenudists.com/forum/viewthread.php?id=1480&post=15509|"Why Am I Sick?" (Nudist Forum)]] - a number of devoted nudists complain about their symptoms of inflammatory disease +  * [[https://www.truenudists.com/forum/viewthread.php?id=1480&post=15509|"Why Am I Sick?" (Nudist Forum)]] - a number of devoted nudists complain about their symptoms of inflammatory disease 
-  * [[http://news.nationalgeographic.com/news/2009/05/090508-sunlight-suicide.html|Too Much Sunshine Spurs Suicides in Arctic, Study Says]] – review of a 2009 //BMC Psychiatry// article,((Björkstén. [[http://www.biomedcentral.com/content/pdf/1471-244x-9-20.pdf|Accentuation of suicides but not homicides with rising latitudes of Greenland in the sunny months]]. //BMC Psychiatry//; 2009. )) which showed that suicide was much more common among Greenland residents in the summer than the winter months +  * [[https://news.nationalgeographic.com/news/2009/05/090508-sunlight-suicide.html|Too Much Sunshine Spurs Suicides in Arctic, Study Says]] – review of a 2009 //BMC Psychiatry// article,((Björkstén. [[https://www.biomedcentral.com/content/pdf/1471-244x-9-20.pdf|Accentuation of suicides but not homicides with rising latitudes of Greenland in the sunny months]]. //BMC Psychiatry//; 2009. )) which showed that suicide was much more common among Greenland residents in the summer than the winter months 
-  * [[http://www.rt.com/news/russia-muslim-sect-satarov-213/|Children born and living without sunlight]] – In 2012, it was learned that 27 children had been living underground as members of a Muslim sect. Many had lived there for their entire lives and had never seen daylight. The conditions of these children was pronounced as "satisfactory" by pediatricians+  * [[https://www.rt.com/news/russia-muslim-sect-satarov-213/|Children born and living without sunlight]] – In 2012, it was learned that 27 children had been living underground as members of a Muslim sect. Many had lived there for their entire lives and had never seen daylight. The conditions of these children was pronounced as "satisfactory" by pediatricians
  
 {{tag> }} {{tag> }}
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 +<nodisp>
 ===== Notes and comments ===== ===== Notes and comments =====
  
   * Legacy content   * Legacy content
-    * http://www.marshallprotocol.com/view_topic.php?id=5035&forum_id=32&jump_to=75781#p75781 f242+    * https://www.marshallprotocol.com/view_topic.php?id=5035&forum_id=32&jump_to=75781#p75781 f242
     * e72     * e72
     * f347     * f347
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 </blockquote> </blockquote>
  
-<blockquote>http://www.tgdaily.com/trendwatch-brief/57832-are-tanning-bed-addicts-like-junkies+<blockquote>https://www.tgdaily.com/trendwatch-brief/57832-are-tanning-bed-addicts-like-junkies
    
 So the next question is whether Vitamin D is addictive. I wonder how many years it will be until somebody studies that :) So the next question is whether Vitamin D is addictive. I wonder how many years it will be until somebody studies that :)
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 ..Trevor.. ..Trevor..
  
-http://www.sciencedaily.com/releases/2010/03/100303162854.htm+https://www.sciencedaily.com/releases/2010/03/100303162854.htm
  
 </blockquote> </blockquote>
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 <blockquote>Med Hypotheses. 2001 Nov;57(5):609-11. <blockquote>Med Hypotheses. 2001 Nov;57(5):609-11.
-Role of endogenous opioids in the effects of light on mood and behavior.(({{pubmed>long:11735320}}))+Role of endogenous opioids in the effects of light on mood and behavior.(({{pmid>long:11735320}}))
 Sher L. Sher L.
 drleosher@aol.com drleosher@aol.com
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 <blockquote> <blockquote>
-http://www.sciencedaily.com/releases/2011/03/110309073938.htm+https://www.sciencedaily.com/releases/2011/03/110309073938.htm
  
 Sunlight Can Influence the Breakdown of Medicines in the Body Sunlight Can Influence the Breakdown of Medicines in the Body
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 From: Dr Trevor Marshall From: Dr Trevor Marshall
 Date: 2011-03-13 11:37:08 Date: 2011-03-13 11:37:08
-Reply: http://marshallprotocol.com/reply.php?topic_id=11829+Reply: https://marshallprotocol.com/reply.php?topic_id=11829
  
 Very interesting. They are still assuming that the seasonal changes in Vit D are due to sun exposure during each season, and not to changes in some other  metabolite as seasons fluctuate (body temperature, for example). Very interesting. They are still assuming that the seasonal changes in Vit D are due to sun exposure during each season, and not to changes in some other  metabolite as seasons fluctuate (body temperature, for example).
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 CONCLUSION: This first study of the distribution of myositis phenotypes and UV radiation exposure in the US showed that UV radiation may modulate the clinical and immunologic expression of autoimmune disease in women. Further investigation of the mechanisms by which these effects are produced may provide insights into pathogenesis and suggest therapeutic or preventative strategies. CONCLUSION: This first study of the distribution of myositis phenotypes and UV radiation exposure in the US showed that UV radiation may modulate the clinical and immunologic expression of autoimmune disease in women. Further investigation of the mechanisms by which these effects are produced may provide insights into pathogenesis and suggest therapeutic or preventative strategies.
 PMID: 19644877</blockquote> PMID: 19644877</blockquote>
-===== References =====  +===== References =====  </nodisp> 
home/othertreatments/sunshine.txt · Last modified: 09.14.2022 by 127.0.0.1
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