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home:pathogenesis:kochs_postulates [05.02.2011] – external edit 127.0.0.1home:pathogenesis:kochs_postulates [09.04.2011] – [Rethinking Koch] paulalbert
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 ===== Still valid? ===== ===== Still valid? =====
 [{{ :home:pathogenesis:robertkoch_cropped.jpg|**Robert Koch** created a series of ground rules to determine whether a given organism can cause a given disease.}}] [{{ :home:pathogenesis:robertkoch_cropped.jpg|**Robert Koch** created a series of ground rules to determine whether a given organism can cause a given disease.}}]
 +
 +<blockquote>When someone talks about imbalance of humors of the miasmic origin of disease, I always detect among listeners the amused tolerance a parent gives to an explanation from his 3-yr-old son. A discourse on Koch’s postulates, on the other hand, is treated with great solemnity. In this light, my premise that there is no more dangerous half-truth among students of disease today than the postulates of Koch may be considered sacrilegious. 
 +
 +//**Robert P. Hanson**// (({{pubmed>long:3286904}}))</blockquote>
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 Koch's contributions were substantial, but his ideas preceded any understanding of genetics or of horizontal gene transfer and made no provision for organisms that were not genetically distinct.   Koch's contributions were substantial, but his ideas preceded any understanding of genetics or of horizontal gene transfer and made no provision for organisms that were not genetically distinct.  
  
-The blind adherence to Koch's postulates precludes a more nuanced understanding of disease: it is in fact a group of genetically indistinct organisms, a [[home:pathogenesis:microbiota|metagenomic microbiota]], which causes and drives chronic disease. +The blind adherence to Koch's postulates precludes a more nuanced understanding of disease: it is in fact a group of genetically indistinct organisms, a [[home:pathogenesis:microbiota|metagenomic microbiota]], which may cause and drive chronic disease. 
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 {{tag> Pathogenesis Study_Design}} {{tag> Pathogenesis Study_Design}}
 ===== Notes and comments ===== ===== Notes and comments =====
home/pathogenesis/kochs_postulates.txt · Last modified: 09.14.2022 by 127.0.0.1
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