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home:pathogenesis:microbiota:interaction [09.09.2012] – [Bacteria] paulalberthome:pathogenesis:microbiota:interaction [09.09.2012] – [Bacteria] paulalbert
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 Expanding on this work, Trost //et al.// performed a pentapeptide and hexapeptide analyses of sequence similarities between bacterial and human DNA.(({{pubmed>long:21487508}})) He demonstrated that there does not exist a single human protein that does not harbor a bacterial pentapeptide or hexapeptide motif; as the team writes, "not even one." Interestingly the team found in a 2012 study that while pathogens and nonpathogens had comparable similarity to the human proteome, pathogens causing chronic infections were found to be more similar to the human proteome than those causing acute infections.(({{pubmed>long:22558081}})) Trost owed this discrepancy to the fact that chronic pathogens are better able to resist immune responses. Expanding on this work, Trost //et al.// performed a pentapeptide and hexapeptide analyses of sequence similarities between bacterial and human DNA.(({{pubmed>long:21487508}})) He demonstrated that there does not exist a single human protein that does not harbor a bacterial pentapeptide or hexapeptide motif; as the team writes, "not even one." Interestingly the team found in a 2012 study that while pathogens and nonpathogens had comparable similarity to the human proteome, pathogens causing chronic infections were found to be more similar to the human proteome than those causing acute infections.(({{pubmed>long:22558081}})) Trost owed this discrepancy to the fact that chronic pathogens are better able to resist immune responses.
  
-Various computational approaches have also been brought to bare on //Salmonella//,(({{pubmed>long:22750305}})) (({{pubmed>long:22589098}})) //Clostridium difficile//, and //Mycobacterium tuberculosis//.(({{pubmed>long:22587966}}))+Surveys of protein-protein interactions have also been completed for //Salmonella//,(({{pubmed>long:22750305}})) (({{pubmed>long:22589098}})) //Clostridium difficile//, and //Mycobacterium tuberculosis//.(({{pubmed>long:22587966}}))
  
  
home/pathogenesis/microbiota/interaction.txt · Last modified: 09.14.2022 by 127.0.0.1
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