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home:pathogenesis:vitamind:cancer [02.10.2019] – [Read more] sallieq | home:pathogenesis:vitamind:cancer [01.14.2020] – [Vitamin D and cancer] sallieq | ||
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* **Interventional studies** - While some randomized controlled trials have suggested that consuming vitamin D reduces rates of cancer, larger and more carefully controlled studies show no such effect. | * **Interventional studies** - While some randomized controlled trials have suggested that consuming vitamin D reduces rates of cancer, larger and more carefully controlled studies show no such effect. | ||
- | * **Studies of vitamin D status** - Many of the studies examining the relationship between vitamin D status and incidence of cancer argue that low levels of 25-D contribute to cancer. This conclusion has been invalidated by larger well-controlled studies. Although the immune system works to downregulate 25-D (25-hydroxyvitamin D) in inflammatory diseases such as cancer, very high levels of 25-D are a clear indication of regular supplementation. | + | * **Studies of vitamin D status** - Many of the studies examining the relationship between vitamin D status and incidence of cancer argue that low levels of 25-D contribute to cancer. This conclusion has been invalidated by larger well-controlled studies. Although the immune system works to downregulate 25-D (25-hydroxyvitamin D) in inflammatory diseases such as cancer, very high levels of 25-D are a clear indication of regular supplementation. |
* **Observational studies** – Some case control studies have found that vitamin D intake seems to increase incidence of certain types of cancer. | * **Observational studies** – Some case control studies have found that vitamin D intake seems to increase incidence of certain types of cancer. | ||
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Researchers at the Chinese Academy of Medical Sciences in China found a similar association between excessive vitamin D intake and esophageal and gastric cancers in men. Male subjects with levels of 25-D in the range of 48.7 ng/ml (which once again suggests heavy supplementation) were much more likely to develop one of the two forms of cancer.(({{pubmed> | Researchers at the Chinese Academy of Medical Sciences in China found a similar association between excessive vitamin D intake and esophageal and gastric cancers in men. Male subjects with levels of 25-D in the range of 48.7 ng/ml (which once again suggests heavy supplementation) were much more likely to develop one of the two forms of cancer.(({{pubmed> | ||
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+ | The following research by //Freedman DM, Looker AC, Abnet CC, Linet MS, Graubard BI// remains unpublished | ||
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- | * [[http://www.landesbioscience.com/journals/dermatoendocrinology/ | + | * [[https://en.wikipedia.org/wiki/Frank_C._Garland|Dr Frank C Garland]] used ecological (population-based) studies to conclude that vitamin D " |
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===== Notes and comments ===== | ===== Notes and comments ===== | ||
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+ | broken link [[http:// | ||