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home:pathogenesis:vitamind:cancer [02.10.2019] – [Evidence that vitamin D intake increases incidence of cancer] sallieqhome:pathogenesis:vitamind:cancer [02.13.2019] – [Notes and comments] sallieq
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 Researchers at the Chinese Academy of Medical Sciences in China found a similar association between excessive vitamin D intake and esophageal and gastric cancers in men. Male subjects with levels of 25-D in the range of 48.7 ng/ml (which once again suggests heavy supplementation) were much more likely to develop one of the two forms of cancer.(({{pubmed>long:17551495}})) A 2011 case control study found that those in the highest 25% of vitamin D intake compared to those in the lowest 25% were significantly more likely to develop oesophageal adenocarcinoma.(({{pubmed>long:21736847}})) Researchers at the Chinese Academy of Medical Sciences in China found a similar association between excessive vitamin D intake and esophageal and gastric cancers in men. Male subjects with levels of 25-D in the range of 48.7 ng/ml (which once again suggests heavy supplementation) were much more likely to develop one of the two forms of cancer.(({{pubmed>long:17551495}})) A 2011 case control study found that those in the highest 25% of vitamin D intake compared to those in the lowest 25% were significantly more likely to develop oesophageal adenocarcinoma.(({{pubmed>long:21736847}}))
  
-The following research by  remains unpublished+The following research by //Freedman DM, Looker AC, Abnet CC, Linet MS, Graubard BI// remains unpublished
 <blockquote>Abstract Vitamin D has been hypothesized to protect against cancer. We followed 16,819 participants in NHANES III from 1988 through 2006, expanding upon an earlier NHANES III study (1988-2000). Using Cox proportional hazard regression models, we examined risk related to baseline serum 25-hydroxyvitamin D (25(OH)D) for total cancer mortality, in both sexes, and by racial/ethnic groups, as well as for site-specific cancers. Because serum was collected in the south in cooler months and the north in warmer months, we examined associations by collection season (“summer/higher latitude” and “winter/lower latitude”). We identified 884 cancer deaths during 225,212 person-years. Overall cancer mortality risks were unrelated to baseline 25(OH)D status in both season/latitude groups, and in non-Hispanic whites, non-Hispanic blacks, and Mexican-Americans. In men, risks were elevated at higher levels (e.g., for ≥100 nmol/L, RR= 1.85 (95% CI=1.02-3.35) compared to <37.5 nmol/L).</blockquote> <blockquote>Abstract Vitamin D has been hypothesized to protect against cancer. We followed 16,819 participants in NHANES III from 1988 through 2006, expanding upon an earlier NHANES III study (1988-2000). Using Cox proportional hazard regression models, we examined risk related to baseline serum 25-hydroxyvitamin D (25(OH)D) for total cancer mortality, in both sexes, and by racial/ethnic groups, as well as for site-specific cancers. Because serum was collected in the south in cooler months and the north in warmer months, we examined associations by collection season (“summer/higher latitude” and “winter/lower latitude”). We identified 884 cancer deaths during 225,212 person-years. Overall cancer mortality risks were unrelated to baseline 25(OH)D status in both season/latitude groups, and in non-Hispanic whites, non-Hispanic blacks, and Mexican-Americans. In men, risks were elevated at higher levels (e.g., for ≥100 nmol/L, RR= 1.85 (95% CI=1.02-3.35) compared to <37.5 nmol/L).</blockquote>
  
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-  * [[http://www.landesbioscience.com/journals/dermatoendocrinology/Grant(3)DE2-2.pdf|Obituary of epidemiologist Dr. Frank Garland]] – Garland used ecological (population-based) studies to conclude that vitamin D "deficiency" increased risk for cancer. One of the most outspoken proponents of supplementation with vitamin D, Garland died in 2010 at the age of 60… from cancer. +  * Obituary  Dr. Frank Garland– Garland used ecological (population-based) studies to conclude that vitamin D "deficiency" increased risk for cancer. One of the most outspoken proponents of supplementation with vitamin D, Garland died in 2010 at the age of 60… from cancer. 
  
  
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 {{tag>pathogenesis Science_behind_vitamin_D}} {{tag>pathogenesis Science_behind_vitamin_D}}
 ===== Notes and comments ===== ===== Notes and comments =====
 +
 +broken link  [[http://www.landesbioscience.com/journals/dermatoendocrinology/Grant(3)DE2-2.pdf|Obituary of epidemiologist Dr. Frank Garland]] 
  
  
home/pathogenesis/vitamind/cancer.txt · Last modified: 09.14.2022 by 127.0.0.1
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