You are here: Welcome to the MPKB » Welcome to the MPKB » Science behind Pathogenesis » Science behind vitamin D » Vitamin D and cancer
Home

Differences

This shows you the differences between two versions of the page.

Link to this comparison view

Both sides previous revisionPrevious revision
Next revision		Previous revision
Next revisionBoth sides next revision
home:pathogenesis:vitamind:cancer [02.13.2019] – [Notes and comments] sallieqhome:pathogenesis:vitamind:cancer [01.14.2020] – [Vitamin D and cancer] sallieq
Line 6: Line 6:
   * **[[home:pathogenesis:vitamind:latitude|Latitude studies]]** - The "latitude studies" are observational, as opposed to interventional, studies, which use ambient solar UV radiation as a proxy for latitude and vitamin D status. For these studies, researchers compare rates of certain major cancers - most notably breast, colorectal and prostate cancer - to rates of sunlight exposure. This group of research has the liability of being wildly inconsistent. The choice to publish research on a specific latitude gradient may be a better proxy for a researcher's bias.   * **[[home:pathogenesis:vitamind:latitude|Latitude studies]]** - The "latitude studies" are observational, as opposed to interventional, studies, which use ambient solar UV radiation as a proxy for latitude and vitamin D status. For these studies, researchers compare rates of certain major cancers - most notably breast, colorectal and prostate cancer - to rates of sunlight exposure. This group of research has the liability of being wildly inconsistent. The choice to publish research on a specific latitude gradient may be a better proxy for a researcher's bias.
   * **Interventional studies** - While some randomized controlled trials have suggested that consuming vitamin D reduces rates of cancer, larger and more carefully controlled studies show no such effect.    * **Interventional studies** - While some randomized controlled trials have suggested that consuming vitamin D reduces rates of cancer, larger and more carefully controlled studies show no such effect. 
-  * **Studies of vitamin D status** - Many of the studies examining the relationship between vitamin D status and incidence of cancer argue that low levels of 25-D contribute to cancer. This conclusion has been invalidated by larger well-controlled studies. Although the immune system works to downregulate 25-D (25-hydroxyvitamin D) in inflammatory diseases such as cancer, very high levels of 25-D are a clear indication of regular supplementation. These studies suggest that consuming large amounts of vitamin D predispose a person to increased incidence of cancer.+  * **Studies of vitamin D status** - Many of the studies examining the relationship between vitamin D status and incidence of cancer argue that low levels of 25-D contribute to cancer. This conclusion has been invalidated by larger well-controlled studies. Although the immune system works to downregulate 25-D (25-hydroxyvitamin D) in inflammatory diseases such as cancer, very high levels of 25-D are a clear indication of regular supplementation. Studies suggest that consuming large amounts of vitamin D predispose a person to increased incidence of cancer.
   * **Observational studies** – Some case control studies have found that vitamin D intake seems to increase incidence of certain types of cancer.   * **Observational studies** – Some case control studies have found that vitamin D intake seems to increase incidence of certain types of cancer.
  
Line 84: Line 84:
  
  
-  * Obituary  Dr. Frank Garland– Garland used ecological (population-based) studies to conclude that vitamin D "deficiency" increased risk for cancer. One of the most outspoken proponents of supplementation with vitamin D, Garland died in 2010 at the age of 60… from cancer. +  * [[https://en.wikipedia.org/wiki/Frank_C._Garland|Dr Frank C Garland]] used ecological (population-based) studies to conclude that vitamin D "deficiency" increased risk for cancer. One of the most outspoken proponents of supplementation with vitamin D, Garland died in 2010 at the age of 60… from cancer. 
  
  
home/pathogenesis/vitamind/cancer.txt · Last modified: 09.14.2022 by 127.0.0.1
© 2015, Autoimmunity Research Foundation. All Rights Reserved.