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home:pathogenesis:vitamind:low25d [07.13.2011] – [Anomalies] paulalbert | home:pathogenesis:vitamind:low25d [09.14.2022] (current) – external edit 127.0.0.1 | ||
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A full understanding of vitamin D metabolism supports the conclusion that elevated 1,25-D and depressed 25-D are a result rather than a cause of the inflammatory process. | A full understanding of vitamin D metabolism supports the conclusion that elevated 1,25-D and depressed 25-D are a result rather than a cause of the inflammatory process. | ||
- | Lower than normal levels of 25-D have been independently associated both with all-cause mortality(({{pubmed> | + | Lower than normal levels of 25-D have been independently associated both with all-cause mortality(({{pmid> |
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- | * acute respiratory tract infections (({{pubmed> | + | * acute respiratory tract infections (({{pmid> |
- | * Addison' | + | * Addison' |
- | * aging skin(({{pubmed> | + | * aging skin(({{pmid> |
- | * alcoholism (({{pubmed> | + | * alcoholism (({{pmid> |
- | * allergic rhinitis (allergies) (({{pubmed> | + | * allergic rhinitis (allergies) (({{pmid> |
- | * Alzheimer' | + | * Alzheimer' |
- | * asthma (({{pubmed> | + | * asthma (({{pmid> |
- | * cancers (({{pubmed> | + | * cancers (({{pmid> |
- | * breast cancer (({{pubmed> | + | * breast cancer (({{pmid> |
- | * colorectal cancer (({{pubmed> | + | * colorectal cancer (({{pmid> |
- | * prostate cancer (({{pubmed> | + | * prostate cancer (({{pmid> |
- | * lung cancer (({{pubmed> | + | * lung cancer (({{pmid> |
- | * non-Hodgkin' | + | * non-Hodgkin' |
- | * ovarian cancer (({{pubmed> | + | * ovarian cancer (({{pmid> |
- | * cardiovascular disease (({{pubmed> | + | * cardiovascular disease (({{pmid> |
- | * celiac disease | + | * celiac disease |
- | * cerebral palsy (({{pubmed> | + | * cerebral palsy (({{pmid> |
- | * chronic liver disease (({{pubmed> | + | * chronic liver disease (({{pmid> |
- | * Chronic obstructive pulmonary disease (({{pubmed> | + | * Chronic obstructive pulmonary disease (({{pmid> |
- | * cognitive dysfunction (({{pubmed> | + | * cognitive dysfunction (({{pmid> |
- | * congestive heart failure (({{pubmed> | + | * congestive heart failure (({{pmid> |
- | * connective tissue-associated interstitial lung diseases(({{pubmed> | + | * connective tissue-associated interstitial lung diseases(({{pmid> |
- | * Crohn' | + | * Crohn' |
- | * cystic fibrosis (({{pubmed> | + | * cystic fibrosis (({{pmid> |
- | * depression (({{pubmed> | + | * depression (({{pmid> |
- | * diabetes, type II (({{pubmed> | + | * diabetes, type II (({{pmid> |
- | * diabetes, type I (({{pubmed> | + | * diabetes, type I (({{pmid> |
- | * elderly(({{pubmed> | + | * elderly(({{pmid> |
- | * epilepsy (({{pubmed> | + | * epilepsy (({{pmid> |
- | * Graves' | + | * Graves' |
- | * kidney disease (({{pubmed> | + | * kidney disease (({{pmid> |
- | * heart failure(({{pubmed> | + | * heart failure(({{pmid> |
- | * HIV (({{pubmed> | + | * HIV (({{pmid> |
- | * inflammatory bowel disease (({{pubmed> | + | * inflammatory bowel disease (({{pmid> |
- | * lupus (systemic lupus erythematosus) (({{pubmed> | + | * lupus (systemic lupus erythematosus) (({{pmid> |
- | * metabolic syndrome((Kevin C. Maki, Martyn R. Rubin, Les G. Wong, Jamie F. McManus, Christopher D. Jensen, John W. Marshall, Andrea Lawless. [[http:// | + | * metabolic syndrome((Kevin C. Maki, Martyn R. Rubin, Les G. Wong, Jamie F. McManus, Christopher D. Jensen, John W. Marshall, Andrea Lawless. [[https:// |
- | * multiple sclerosis (({{pubmed> | + | * multiple sclerosis (({{pmid> |
- | * myocardial infarction (heart attack) (({{pubmed> | + | * myocardial infarction (heart attack) (({{pmid> |
- | * obesity (({{pubmed> | + | * obesity (({{pmid> |
- | * osteoarthritis (({{pubmed> | + | * osteoarthritis (({{pmid> |
- | * osteoporosis and osteopenia (({{pubmed> | + | * osteoporosis and osteopenia (({{pmid> |
- | * pain (myalgia) (({{pubmed> | + | * pain (myalgia) (({{pmid> |
- | * Parkinson' | + | * Parkinson' |
- | * pelvic floor disorders (({{pubmed> | + | * pelvic floor disorders (({{pmid> |
- | * schizophrenia (({{pubmed> | + | * schizophrenia (({{pmid> |
- | * slow psychomotor processing speed ((Lee DM, Tajar A //et al//. [[http:// | + | * slow psychomotor processing speed ((Lee DM, Tajar A //et al//. [[https:// |
- | * stroke (({{pubmed> | + | * stroke (({{pmid> |
- | * tuberculosis (({{pubmed> | + | * tuberculosis (({{pmid> |
- | * undifferentiated connective tissue disease (({{pubmed> | + | * undifferentiated connective tissue disease (({{pmid> |
- | * vaginosis(({{pubmed> | + | * vaginosis(({{pmid> |
===== Anomalies ===== | ===== Anomalies ===== | ||
+ | [{{ : | ||
+ | |||
+ | * **mortality in the Danish population** – A 2012 study of 247,574 subjects found that both lower and higher levels of 25-D were associated with an increased likelihood of mortality (right).(({{pmid> | ||
+ | * **U-shaped relationship between vitamin D levels and long-term outcome.** – In a 5 year follow-up of survivors of acute myocardial infarction patients with vitamin D< | ||
* **risk of breast cancer** – In a 2011 study of nurses who were predominantly premenopausal, | * **risk of breast cancer** – In a 2011 study of nurses who were predominantly premenopausal, | ||
- | * **risk of prostate cancer** – In a 2008 nested case-control study appearing in //Journal of the National Cancer Institute//, | + | * **risk of prostate cancer** – In a 2008 nested case-control study appearing in //Journal of the National Cancer Institute//, |
- | * **risk of pancreatic cancer** – Patients with the highest levels of 25-D were at greatest risk of pancreatic cancer.(({{pubmed> | + | * **risk of pancreatic cancer** – Patients with the highest levels of 25-D were at greatest risk of pancreatic cancer.(({{pmid> |
- | * **some rarer cancers**(({{pubmed> | + | * **some rarer cancers**(({{pmid> |
- | * **cancer mortality** – A 2010 longitudinal study found that both high and low concentrations of plasma 25(OH)D were associated with elevated risks of overall and cancer mortality, and low concentrations are associated with cardiovascular mortality.(({{pubmed> | + | * **cancer mortality** – A 2010 longitudinal study found that both high and low concentrations of plasma 25(OH)D were associated with elevated risks of overall and cancer mortality, and low concentrations are associated with cardiovascular mortality.(({{pmid> |
- | * **neonatal vitamin D status and risk of schizophrenia** – Danish neonates with the highest measurable levels of 25-D had a two-fold elevated risk of developing schizoprhenia. | + | * **neonatal vitamin D status and risk of schizophrenia** – Danish neonates with the highest measurable levels of 25-D had a two-fold elevated risk of developing schizoprhenia. |
- | * **atherosclerosis in African Americans** – Vitamin D is widely used to treat patients with osteoporosis and/or low vitamin D levels based on a medically accepted normal range. This " | + | * **atrial fibrillation** – According to results shared at a [[https:// |
+ | * **atherosclerosis in African Americans** – Vitamin D is widely used to treat patients with osteoporosis and/or low vitamin D levels based on a medically accepted normal range. This " | ||
- | ===== Notes and comments ===== | ||
- | TECHEDIT | ||
- | {{:home:pathogenesis: | + | {{tag>pathogenesis |
+ | < | ||
+ | ===== Notes and comments ===== | ||
- | < | + | --- //Sallie Q 09.16.2016// added 2016 report on U-shape curve high up on list of anomalies |
- | http://www.sciencedaily.com/releases/2010/ | + | |
- | A recent study accepted for publication in The Endocrine Society' | + | {{: |
- | This new study however found a U-SHAPED RELATIOSHIP between vitamin D levels and frailty; older women with vitamin D levels higher than 30 ng/ml and those with levels lower than 20 ng/ml were more likely to be frail. | ||
- | “Vitamin D supplementation has grown in popularity, yet the association between vitamin D status and risk of adverse health outcomes in older adults is uncertain," | + | ===== References =====</ |
- | " | ||
- | </ | ||
- | ===== References ===== |