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home:physicians:vitamin_d_leaflet [06.11.2018] – [The Innate Immune response] sallieq | home:physicians:vitamin_d_leaflet [06.11.2018] – [The body controls activity of the VDR through regulation of the Vitamin D Metabolites] sallieq | ||
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- | Although early stage autoimmune disease often succumbs to antibiotic therapy, antibiotics appear to lose utility as disease progresses. Recent sequencing of microbial DNA has confirmed that some pathogens ensure their persistence by reducing expression of, and transcription by, the VDR nuclear receptor, which is at the heart of the human innate immune system. | + | Although early stage autoimmune disease often succumbs to antibiotic therapy, antibiotics appear to lose utility as disease progresses. Recent sequencing of microbial DNA has confirmed that some pathogens ensure their persistence by reducing expression of, and transcription by, the VDR nuclear receptor, which is at the heart of the human innate immune system. |
Only in homo sapiens is the VDR responsible for expression of the Cathelicidin antimicrobial peptide, the primary defene of the intra-phagocytic innate immune system. | Only in homo sapiens is the VDR responsible for expression of the Cathelicidin antimicrobial peptide, the primary defene of the intra-phagocytic innate immune system. |