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home:publications:blaney_autoimmunity_2010 [06.14.2010] – paulalberthome:publications:blaney_autoimmunity_2010 [01.03.2012] – external edit 127.0.0.1
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 Sixth, low dose, pulsed bacteriostatic antibiotics, taken over a prolonged time are safe and are not associated with development of bacterial resistance or overgrowth of other pathogens such as C. difficile or candida albicans. Sixth, low dose, pulsed bacteriostatic antibiotics, taken over a prolonged time are safe and are not associated with development of bacterial resistance or overgrowth of other pathogens such as C. difficile or candida albicans.
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 ==== Slide 12 ==== ==== Slide 12 ====
  
  
 Finally, persistent infection is a likely cause of some autoimmune and chronic diseases that are associated with immune imbalance. The recognized capacity of bacteria to resist lysosomal degradation, to be able to transform into cell wall deficient forms, to communicate and share information, to create persister cells and the ability to establish biofilms, all enable persistence. Any or all of these actions could then have a profound impact on immune capacity and tolerance. If so, it will explain some of the mysteries still existing in autoimmunity and open new opportunities for therapy. Finally, persistent infection is a likely cause of some autoimmune and chronic diseases that are associated with immune imbalance. The recognized capacity of bacteria to resist lysosomal degradation, to be able to transform into cell wall deficient forms, to communicate and share information, to create persister cells and the ability to establish biofilms, all enable persistence. Any or all of these actions could then have a profound impact on immune capacity and tolerance. If so, it will explain some of the mysteries still existing in autoimmunity and open new opportunities for therapy.
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 ===== Notes and comments ===== ===== Notes and comments =====
  
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 ===== References ===== ===== References =====
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