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home:publications:marshall_days_of_molecular_medicine_2006 [01.21.2009] – paulalbert | home:publications:marshall_days_of_molecular_medicine_2006 [07.04.2022] (current) – external edit 127.0.0.1 | ||
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+ | ~~NOTOC~~ | ||
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+ | ====== Poster - VDR Nuclear Receptor competence is the key to recovery from chronic inflammatory and autoimmune disease ====== | ||
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+ | **Type:** Abstract presentation\\ | ||
+ | **Presented by:** Trevor Marshall, PhD\\ | ||
+ | **Conference: | ||
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+ | **Additional content:** [[https:// | ||
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+ | ===== Abstract ===== | ||
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+ | The VDR Nuclear Receptor is at the heart of the human innate immunity, responsible for TLR2, TLR4, CAMP TACO and IL2 expression [1]. During Th1 immune challenge, the VDR is activated by the endogenous secosteroid 1,25 dihydroxyvitamin D. We have previously described how intra-phagocytic bacterial pathogens are responsible for much chronic inflammatory disease [2,3], and our phase 2 study results have confirmed this pathogenesis. In order to induce recovery from chronic inflammatory disease, it is necessary to restore VDR function by removing all exogenous sources of the secosteroid we call ‘Vitamin-D, | ||
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+ | RESULTS: To date we have demonstrated recovery from Hashimoto’s Thyroiditis, | ||
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