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home:social:stress [11.27.2010] – paulalbert | home:social:stress [04.28.2011] – [Factors driving chronic disease] paulalbert | ||
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Not unlike vitamin D metabolism, the human stress response is governed by a sophisticated hormonal system, one which is also dysregulated in patients with chronic inflammatory diseases. Successful management of both stressors and a patient' | Not unlike vitamin D metabolism, the human stress response is governed by a sophisticated hormonal system, one which is also dysregulated in patients with chronic inflammatory diseases. Successful management of both stressors and a patient' | ||
- | Physical stress or trauma has also been accepted as a contributor for several chronic diseases | + | Physical stress or trauma has also been accepted as a partial |
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===== Psychological stress and immune function ===== | ===== Psychological stress and immune function ===== | ||
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{{section>: | {{section>: | ||
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- | ===== Psychological stress and disease ===== | ||
+ | ===== Psychological stress and disease ===== | ||
- | Some researchers have concluded that stressors trigger disease. These researchers point to retrospective studies, which have found that a high proportion of certain kinds of patients reported uncommon emotional stress before disease onset.(({{pubmed> | + | Some researchers have concluded that stressors |
* periodontal disease (({{pubmed> | * periodontal disease (({{pubmed> | ||
* Graves' | * Graves' | ||
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There are a number of circumstances inherent to war which appear to drive the prevalence of chronic disease. | There are a number of circumstances inherent to war which appear to drive the prevalence of chronic disease. | ||
- | * **Acquisition of new pathogens** – Any event which brings together diverse groups of humans in new environments allows for the acquisition and sharing of chronic pathogens – especially war with its close quarters, and unsanitary and undersanitary conditions. Studying metabolites in urine, Dumas //et al// showed that three geographically distinct populations seemed to each have a distinct microbiota. Interestingly, | + | * **Acquisition of new pathogens** – As discussed in a [[http:// |
* **Physical trauma and stress** – Fibromyalgia patients are more likely to report significant physical trauma prior to disease onset.(({{pubmed> | * **Physical trauma and stress** – Fibromyalgia patients are more likely to report significant physical trauma prior to disease onset.(({{pubmed> | ||
* **Psychological stress** – Studies have linked traumatic stress exposures to a wide variety of conditions.(({{pubmed> | * **Psychological stress** – Studies have linked traumatic stress exposures to a wide variety of conditions.(({{pubmed> | ||
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+ | * explain car accidents, etc. as disease triggers1 2 Blaney: “I have observed in many patients that an important precipitator of increased Th1 disease is physical injury. My speculation is that the physical trauma further activated AT1 due to the wound response, suppressing the immune system further and allowing increased bacterial growth.” | ||
=====References===== | =====References===== |