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home:symptoms:neurological:cognitive [05.29.2020] – [Notes and comments] sallieq | home:symptoms:neurological:cognitive [09.14.2022] (current) – external edit 127.0.0.1 | ||
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Cognitive dysfunction (also known as brain fog) is the loss of intellectual functions such as thinking, remembering, | Cognitive dysfunction (also known as brain fog) is the loss of intellectual functions such as thinking, remembering, | ||
- | According to the Marshall Pathogenesis, | + | According to the Marshall Pathogenesis, |
Like all symptoms of inflammatory disease, cognitive dysfunction may temporarily increase during periods of immunopathology. Cognitive dysfunction can be managed using the [[home: | Like all symptoms of inflammatory disease, cognitive dysfunction may temporarily increase during periods of immunopathology. Cognitive dysfunction can be managed using the [[home: | ||
- | Some studies seem to suggest that sick women experience cognitive dysfunction more frequently and more severely than their male counterparts.(({{pubmed> | + | Some studies seem to suggest that sick women experience cognitive dysfunction more frequently and more severely than their male counterparts.(({{pmid> |
===== Management of symptoms ===== | ===== Management of symptoms ===== | ||
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- | * **cognitive and functional decline often follow severe sepsis** – The researchers focused their attention on 516 individuals who survived hospitalization for severe sepsis and 4517 who survived a nonsepsis hospitalization. The average age of survivors at hospitalization was 76.9 years. Following severe sepsis hospitalization, | + | * **cognitive and functional decline often follow severe sepsis** – The researchers focused their attention on 516 individuals who survived hospitalization for severe sepsis and 4517 who survived a nonsepsis hospitalization. The average age of survivors at hospitalization was 76.9 years. Following severe sepsis hospitalization, |
- | * **aging immune cells in animal models** – The decline in brain function associated with disease and old age could be due to the decline in the function of immune cells, which is likely caused by infection. As described in New Scientist, prompted by studies suggesting immune responses can help repair the nervous system, Jonathan Kipnis and colleagues at the University of Virginia created mice that lack CD4 cells, a kind of T-cell. They found the mice performed extremely poorly in tasks involving learning and memory, but when they were injected with CD4 cells from healthy mice, their memories improved.(({{pubmed> | + | * **aging immune cells in animal models** – The decline in brain function associated with disease and old age could be due to the decline in the function of immune cells, which is likely caused by infection. As described in New Scientist, prompted by studies suggesting immune responses can help repair the nervous system, Jonathan Kipnis and colleagues at the University of Virginia created mice that lack CD4 cells, a kind of T-cell. They found the mice performed extremely poorly in tasks involving learning and memory, but when they were injected with CD4 cells from healthy mice, their memories improved.(({{pmid> |
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{{tag> | {{tag> | ||
+ | < | ||
===== Notes and comments ===== | ===== Notes and comments ===== | ||
broken links | broken links | ||
- | [[http:// | + | [[https:// |
- | * [[http:// | + | * [[https:// |
- | {{: | + | {{: |
- | [[http:// | + | [[https:// |
As described in New Scientist, prompted by studies suggesting immune responses can help repair the nervous system, Jonathan Kipnis and colleagues at the University of Virginia created mice that lack CD4 cells, a kind of T-cell. | As described in New Scientist, prompted by studies suggesting immune responses can help repair the nervous system, Jonathan Kipnis and colleagues at the University of Virginia created mice that lack CD4 cells, a kind of T-cell. | ||
* Legacy content | * Legacy content | ||
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- | [[http:// | + | [[https:// |
+ | |||
+ | ===== References =====</ | ||
- | ===== References ===== |