Home

Differences

This shows you the differences between two versions of the page.

Link to this comparison view

Both sides previous revision Previous revision
home:symptoms:neurological [02.14.2019]
sallieq [Blood-brain barrier is leaky]
home:symptoms:neurological [03.15.2019] (current)
sallieq [Blood-brain barrier is leaky]
Line 49: Line 49:
  
 One prominent example of a microbe that passes the blood-brain barrier is //​Borrelia//​.(({{pubmed>​long:​ 15664945}})) One prominent example of a microbe that passes the blood-brain barrier is //​Borrelia//​.(({{pubmed>​long:​ 15664945}}))
 +
  
 The brain immune system, which consists mainly of astrocytes, microglia and infiltrating immune cells, is quiescent normally, but it is activated in response to pathophysiological events such as ischemia, trauma, inflammation and infection. ​ (({{pubmed>​long: ​   16125796}})) The brain immune system, which consists mainly of astrocytes, microglia and infiltrating immune cells, is quiescent normally, but it is activated in response to pathophysiological events such as ischemia, trauma, inflammation and infection. ​ (({{pubmed>​long: ​   16125796}}))
 +
 + Mast cells are located in close proximity to the vasculature,​ and vasoactive mediators released upon their activation can promote endothelial activation leading to blood brain barrier (BBB) dysfunction. ​ (({{pubmed>​long: ​   30837844}}))  ​
  
  
home/symptoms/neurological.txt · Last modified: 03.15.2019 by sallieq
© 2015, Autoimmunity Research Foundation. All Rights Reserved.