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home:symptoms:skin [05.31.2011] – paulalbert | home:symptoms:skin [09.02.2012] – paulalbert | ||
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- | ====== Skin symptoms | + | ====== Skin conditions |
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+ | ===== Skin microbiome ===== | ||
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+ | A decade ago, Chiller //et al.// concluded, “The skin is a poor media for bacteria given the large number of inherent defense mechanisms.”(({{pubmed> | ||
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+ | Novel insights are being revealed about the extent to which skin microbiota affects health. For example, odors produced by skin microbiota are attractive to mosquitoes as shown by //in vitro// studies, and variation in bacterial species on the human skin may explain the variation in mosquito attraction between humans.(({{pubmed> | ||
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+ | |||
+ | ===== Types ===== | ||
+ | |||
+ | * atopic dermatitis | ||
* edema (swelling) | * edema (swelling) | ||
- | * lumps | + | * lumps |
- | * pruritus (itchiness) | + | * lupus pernio |
- | * rash | + | |
- | * vitilligo | + | |
- | * shingles | + | |
* odor | * odor | ||
+ | * psoriasis | ||
+ | * rash and itching (pruritus) | ||
+ | * shingles | ||
+ | * vitilligo | ||
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+ | ==== Atopic dermatitis ==== | ||
+ | |||
+ | < | ||
+ | 4. | ||
+ | Differential mRNA expression of antimicrobial peptides and proteins in atopic dermatitis as compared to psoriasis vulgaris and healthy skin. | ||
+ | Gambichler T, Skrygan M, Tomi NS, Othlinghaus N, Brockmeyer NH, Altmeyer P, Kreuter A. | ||
+ | Int Arch Allergy Immunol. 2008; | ||
+ | PMID: 18446049 [PubMed - indexed for MEDLINE] | ||
+ | Related citations Remove from clipboard | ||
+ | |||
+ | |||
+ | The role of antimicrobial peptides in human skin and in skin infectious diseases. | ||
+ | Schittek B, Paulmann M, Senyürek I, Steffen H. | ||
+ | Infect Disord Drug Targets. 2008 Sep; | ||
+ | PMID: 18782030 [PubMed - indexed for MEDLINE] | ||
+ | |||
+ | |||
+ | </ | ||
+ | |||
+ | |||
+ | |||
- | ===== Vitiligo | + | ==== Vitiligo ==== |
The skin symptom of vitilligo has been reported by persons on the MP. Some have reported improvement while on the MP. It may simply be another symptom of autoimmune disease. | The skin symptom of vitilligo has been reported by persons on the MP. Some have reported improvement while on the MP. It may simply be another symptom of autoimmune disease. | ||
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* [[http:// | * [[http:// | ||
* [[http:// | * [[http:// | ||
- | * | + | |
- | + | ||
+ | ===== Comorbidities ===== | ||
< | < | ||
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- | {{tag> | + | ===== Manifestations of immunopathology |
- | + | ||
- | ===== Notes and comments | + | |
- | REVISE | + | |
- | + | ||
- | * Legacy content | + | |
- | + | ||
- | s290: | + | |
- | + | ||
- | Cutaneous manifestations of Th1 inflammation | + | |
Cutaneous immunopathology | Cutaneous immunopathology | ||
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Cosmetics may help cover a discoloration. Use moisturizers as needed and avoid sunlight and extreme heat. Consult your physician if you continue to have concerns. | Cosmetics may help cover a discoloration. Use moisturizers as needed and avoid sunlight and extreme heat. Consult your physician if you continue to have concerns. | ||
- | Lupus pernio | + | ===== Lupus pernio |
Lesions on the face that occur or exacerbate when it's cold or windy can be what is called lupus pernio. Lupus Pernio is a skin manifestation of sarcoidosis. Lupus Pernio is not another disease (and is not related to lupus), it's simply a name for the red-to purplish lesions that can appear on the nose, face, ears or hands of sarcoidosis patients. These lesions can occur when the nose, face or hands are exposed to cold or wind, so it's a good idea for sarcies to keep these areas protected from wind and cold. Avoiding exposure to bright lights is also an important preventative measure. | Lesions on the face that occur or exacerbate when it's cold or windy can be what is called lupus pernio. Lupus Pernio is a skin manifestation of sarcoidosis. Lupus Pernio is not another disease (and is not related to lupus), it's simply a name for the red-to purplish lesions that can appear on the nose, face, ears or hands of sarcoidosis patients. These lesions can occur when the nose, face or hands are exposed to cold or wind, so it's a good idea for sarcies to keep these areas protected from wind and cold. Avoiding exposure to bright lights is also an important preventative measure. | ||
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Lupus pernio is said to be the skin lesion most characteristic (a diagnostic indicator) of sarcoidosis, | Lupus pernio is said to be the skin lesion most characteristic (a diagnostic indicator) of sarcoidosis, | ||
- | -My experience with lupus pernio is that it flares with exposure to light plus cold and wind. I suspect you have still been having a good bit of cool wind and weather in your part of the world. You may need to keep your nose better protected. I know that's hard to do, so if nothing else, you can stay indoors during daytime as much as possible and wrap a scarf around your nose if it is cool or windy. | + | ==== Patients experiences ==== |
+ | |||
+ | < | ||
+ | |||
+ | Warning of the risk of scarring, whether on the skin or in the lungs, is a common tactic to pressure patients to use the treatment a physician prefers. Lupus pernio has a reputation for being difficult to treat. In reality, the doctor has no way to know whether you will scar. Certainly I sustained no scars from my winter bouts with lupus pernio. | ||
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+ | // | ||
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+ | |||
- | Warning of the risk of scarring, whether on the skin or in the lungs, is a common tactic to pressure patients to use the treatment a physician prefers. Lupus pernio has a reputation for being difficult to treat. In reality, the doctor has no way to know whether you will scar. Certainly I sustained no scars from my winter bouts with lupus pernio. ~Belinda | ||
Skin rash | Skin rash | ||
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Sarcoid skin lesions can be painful, itchy, oozy or dry and peeling. They can also make your hair fall out. You can find more information and lots of pictures of skin sarcoidosis (to compare with your rashes) in the thread "Skin Sarc, What Does it Look Like?" or Images of cutanenous sarcoidosis. | Sarcoid skin lesions can be painful, itchy, oozy or dry and peeling. They can also make your hair fall out. You can find more information and lots of pictures of skin sarcoidosis (to compare with your rashes) in the thread "Skin Sarc, What Does it Look Like?" or Images of cutanenous sarcoidosis. | ||
- | Members' | ||
- | -Ive been on the MP now for 1 year this month. I have skin lesions on my face and i noticed them get better, texture and inflammation wise, when i started the the first meds, olmersartan and then the first antibiotic. Now texture has greatly improved, lesions were very dry, inflamed and flakey and hurt alot when touched before starting MP. A few months ago i noticed, not only have they impoved in texture but some are actually starting to fade on some sides. I've gotten a few new lesions since starting but there also improving. None have actually completely gone or disappeared but i think now there starting to show signs of great improvement ahead and i feel that from the improvements i have witnessed that they will fade away and leave no marks, some time in the near future. I havent yet reached the the optimal level of all antibiotics yet but hopeful will in November and then stay at that optimal level for the next 12-24 months, so im sure i will see more improvement and disappearance of the lesion. ~sd | ||
+ | ===== Skin lesions ===== | ||
- | Last edited | + | ==== Patients experiences ==== |
+ | |||
+ | < | ||
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+ | //**sd**, MarshallProtocol.com//</ | ||
- | * s290 | ||
- | f217: | ||
- | The lumps under my skin are worse. Will the MP make them go away? | ||
The lumps under my skin are worse. Will the MP make them go away? | The lumps under my skin are worse. Will the MP make them go away? | ||
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and Why Does the Body Make Granulomas? | and Why Does the Body Make Granulomas? | ||
- | My lymph nodes are growing. Is this normal? has Member experiences also. | ||
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- | -------------------------------------------------------------------------------- | ||
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- | Generated from this source: http:// | ||
- | WARNING: | ||
- | Migration code: F217 | ||
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- | * f217 | ||
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- | f92: | ||
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- | Posted: Thu Jan 24th, 2008 15: | ||
- | Quote | ||
- | Reply | ||
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- | [filelink] | ||
- | Improvements in skin conditions | ||
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- | -Another great thing that is happening to me is my granulomatous raised red skin lesions that had covered 80% of by body has literally cleared up. It's flattened out and browned back to nearly my original olive skin colour. | ||
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- | All this has made me contact the skin and cancer foundation of Australia where I originally went and got my diagnosis of Sarcoid 8 years ago. I spoke to them and told them about all this. It flew over there heads but they are willing to see me because my case was very interesting for them at the time and I think they want to know how all this stuff works because I'm the living proof of the MP working.~Simon Elrahi | ||
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- | I had many skin lesions come and go in first year of MP, and just two month ago had a large raised lesion (AK) just slough off and disappear. ~ P.B. | ||
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- | I have had some interesting changes in areas where I had sun damaged skin. Particularly my neckline and the backs of my hands. At first, the MP seemed to exacerbate the redness in these areas, especially my neckline. For the first two years the skin was very red and irritated. But recently, I've started to notice it feeling much softer to the touch. There seems to be a new layer of fat making the skin feel much softer and the irritation has disappeared. I find myself constantly wanting to touch this skin it is so soft...it is an amazing difference.~ Aunt Diana | ||
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- | * f92 | ||
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- | f89: | ||
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- | I've developed a rash/ | ||
+ | ===== Managing skin symptoms ===== | ||
"Skin eruptions" | "Skin eruptions" | ||
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You may get relief from intolerable itching with Cyproheptadine, | You may get relief from intolerable itching with Cyproheptadine, | ||
+ | ===== Other treatments ===== | ||
+ | ==== Steroids ==== | ||
Topical steroids | Topical steroids | ||
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See also: | See also: | ||
- | Candidiasis (yeast infection) | ||
- | Scroll down for information about other skin problems and suggested | + | ===== Over the counter |
- | Last edited on Sun Jul 27th, 2008 00:52 by Meg Mangin R.N. | + | ==== Itchy skin ==== |
- | ____________________ | + | < |
- | Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician. | + | |
- | * f89 | + | |
- | f90: | + | // |
- | Other skin problems | + | < |
+ | // | ||
- | Itchy skin | + | < |
- | Benadryl cream helps the bits that aren't raw. A little hydrocortisone on a few places to make life bearable, but as little as possible. | + | //**Mel (shadowfeet)**, MarshallProtocol.com//</ |
- | The thing that finally calmed my face itch down was washing with soap and water and a cream called Florasone | + | < |
- | -I have had a skin rash on my hands a couple of times since starting the MP, that was similar to yours by the sound of it. I found that a low dose of antihistamine helped to reduce the itching. | + | //**Gail**, MarshallProtocol.com//</ |
- | -I have been using a honey & blackberry soap (from Walmart: in the dish soap area for sensitive skin) My skin sensitivity has eased some and the skin issues that I was having on the backs of my knees have disappeared...no more itching! | ||
- | Dry, crusty | + | ==== Dry skin ==== |
- | Sween makes a cream called Atrac-tain which contains urea and lactic acid to gently exfoliate the skin. It works remarkably well to remove crusty tissue and restore smooth skin. Try it on a small area first to make sure you are not sensitive to any of the ingredients. It can usually be purchase at a local pharmacy. | + | < |
- | Dry skin | + | //**Meg**, MarshallProtocol.com//</ |
- | The Body Shop has a dry olive oil mist that comes in a spray mister....I really like it. It's not quite as oily as olive oil. You may want to try it. I got mine online at bodyshop.com . ~ Aunt Diana | + | < |
- | The chlorine in tap water can be very drying to the skin. You can purchase, for about $45, a charcoal filter for your shower-head which will filter it out. I think it makes a world of difference, you (and anybody else with dry skin) might want to give this a try. ~ Joy | + | //**Joy**, MarshallProtocol.com//</ |
- | Itchy scalp | ||
- | I had lots of itching and breaking out (skin sarcs) got worse...all herx sxs. Benadryl cream (slathered entire areas) | + | < |
+ | |||
+ | //**Aunt Diana**, MarshallProtocol.com//</ | ||
- | Psoriasis | ||
- | I've had lots of experience with psoriasis (which looks like sarc lesions, BTW). I've found a cream that helps it feel better. It's a combo of mango and shea butter that I buy at Walmart, made by Tree Hut. It's very soothing. | + | ==== Itchy scalp ==== |
- | Raw skin lesions | + | < |
- | I've had good results applying Campho-Phenique (for lip Cold Sores) on my raw skin lesions when not able to use Benadryl. This OTC medicine stops the itching and burning fast. ~Donna | + | // |
- | Scars, skin tags and moles | ||
- | I have several scars on my hands that have turned a little brown some of them even a little red. One of them has been there since I was a kid and it is even starting to level out it used to stick up a little bit. I've had fifteen or more skin tags fall off. I've had small moles disappear and my larger ones are about the size of my small ones. Mine all started improving in the higher up on phase two. I am having all kind of crazy stuff on my skin happen right now dark spots coming and going, rashes, try spots but none of it is lasting more than a couple weeks. ~Ival | ||
- | About a month ago I had a mole on my arm just turn to a sort of sludge and dissapear. It felt itchy one day and I just wiped it off with a handkerchief. It left a small hole (about 6mm by 9mm), very clean on the bottom, and that healed up quickly and looks like it will leave no scar. I'm assuming my immune system took a dislike to this mole! | + | |
+ | |||
+ | |||
+ | ==== Raw skin lesions ==== | ||
+ | |||
+ | < | ||
+ | |||
+ | // | ||
+ | |||
+ | |||
+ | |||
+ | ==== Scars, skin tags and moles ==== | ||
+ | |||
+ | |||
+ | < | ||
+ | |||
+ | //**Ival**, MarshallProtocol.com//</ | ||
+ | |||
+ | < | ||
Just FYI, the other two chronic lesions on my arms have also healed since I started the MP (they were sores that scarred up, then they would crack open and bleed spontaneously and then erode to a sore again, over and over for about 3 years) There is a very little scarring there now, but it's just a mark and not the thick knob of scar that it used to form between breakouts. ~Knochen | Just FYI, the other two chronic lesions on my arms have also healed since I started the MP (they were sores that scarred up, then they would crack open and bleed spontaneously and then erode to a sore again, over and over for about 3 years) There is a very little scarring there now, but it's just a mark and not the thick knob of scar that it used to form between breakouts. ~Knochen | ||
- | A few days ago I noticed several small red, raw spots on the side of my face. I wondered how they got there. | + | A few days ago I noticed several small red, raw spots on the side of my face. I wondered how they got there. |
+ | |||
+ | //**Carol**, MarshallProtocol.com//</ | ||
+ | |||
+ | |||
Hypopigmentation | Hypopigmentation | ||
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Many of the white areas on my skin have disappeared! ~Alayne | Many of the white areas on my skin have disappeared! ~Alayne | ||
- | See Vitiligo | + | |
Dark pigment changes | Dark pigment changes | ||
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those very itchy, scabby patches are completely gone. ~Adrianne | those very itchy, scabby patches are completely gone. ~Adrianne | ||
+ | |||
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Bunion | Bunion | ||
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+ | ===== Patients experiences ===== | ||
+ | ==== Improvements in skin conditions ==== | ||
- | < | + | < |
- | Authors: | + | All this has made me contact the skin and cancer foundation of Australia where I originally went and got my diagnosis of Sarcoid 8 years ago. I spoke to them and told them about all this. It flew over there heads but they are willing to see me because my case was very interesting for them at the time and I think they want to know how all this stuff works because I'm the living proof of the MP working.~Simon Elrahi |
- | Verhulst, NO; Takken, W; Dicke, M; Schraa, G; Smallegange, | + | |
- | Author Full Names: | + | I had many skin lesions come and go in first year of MP, and just two month ago had a large raised lesion (AK) just slough off and disappear. |
- | Verhulst, Niels O.; Takken, Willem; Dicke, Marcel; Schraa, Gosse; Smallegange, | + | |
- | Source: | + | //**P.B.**, MarshallProtocol.com//</ |
- | FEMS MICROBIOLOGY ECOLOGY 74 (1): 1-9 OCT 2010 | + | |
- | Language: | ||
- | English | ||
- | Document Type: | + | < |
- | Review | + | |
- | Author Keywords: | + | //**Aunt Diana**, MarshallProtocol.com//</ |
- | skin microbiota; disease vectors; HLA; volatiles; odours; Anopheles gambiae | + | |
- | KeyWords Plus: | ||
- | HUMAN AXILLARY ODOR; COMPLETE GENOME SEQUENCE; HUMAN-BODY ODOR; GAS CHROMATOGRAPHY/ | ||
- | Abstract: | ||
- | Microbiota on the human skin plays a major role in body odour production. The human microbial and chemical signature displays a qualitative and quantitative correlation. Genes may influence the chemical signature by shaping the composition of the microbiota. Recent studies on human skin microbiota, using 16S rRNA gene sequencing, found a high inter- and intrapersonal variation in bacterial species on the human skin, which is relatively stable over time. Human body odours mediate the attraction of mosquitoes to their blood hosts. Odours produced by skin microbiota are attractive to mosquitoes as shown by in vitro studies, and variation in bacterial species on the human skin may explain the variation in mosquito attraction between humans. Detailed knowledge of the ecology and genetics of human skin microbiota is needed in order to unravel the evolutionary mechanisms that underlie the interactions between mosquitoes and their hosts. | ||
- | </ | ||
- | < | + | |
- | A diversity profile of the human skin microbiota. | + | |
- | Grice EA, Kong HH, Renaud G, Young AC; NISC Comparative Sequencing Program, Bouffard GG, Blakesley RW, Wolfsberg TG, Turner ML, Segre JA. | + | |
- | Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA. | + | |
- | Abstract | + | |
- | The many layers | + | |
- | PMID: 18502944 | + | |
+ | {{tag> | ||
+ | |||
+ | |||
+ | ===== Notes and comments ===== | ||
- | Many lines of evidence suggest a role for microorganisms even in noninfectious skin diseases, such as atopic dermatitis (AD; eczema), rosacea, psoriasis, and acne (Holland et al. 1977; Thomsen et al. 1980;Till et al. 2000; Paulino et al. 2006).</ | + | ===== References ===== |