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home:tests:lipids [11.05.2010] – external 127.0.0.1home:tests:lipids [01.03.2012] – external edit 127.0.0.1
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   * triglycerides   * triglycerides
  
-In many of the diseases the Marshall Protocol (MP) treats, patients may present with elevated cholesterol. Traditionally, it has been assumed that the elevated cholesterol is causing or contributing to the disease process. However, the alternate hypothesis is no less plausible; in certain inflammatory diseases, the body may be deliberately upregulating levels of cholesterol in order to better manage the disease process. Increasing evidence suggests that this alternative explanation may be true.(({{pubmed>long:14631060}})) (({{pubmed>long:20377753}})) For example, a 2010 study found that several bacterial taxa in the oral cavity and the gut correlated with plasma cholesterol levels.(({{pubmed>long:20937873}})) +In many of the diseases the Marshall Protocol (MP) treats, patients may present with elevated cholesterol. Traditionally, it has been assumed that the elevated cholesterol is causing or contributing to the disease process. However, the alternate hypothesis is no less plausible; in certain inflammatory diseases, the body may be deliberately upregulating levels of cholesterol in order to better manage the disease process. Increasing evidence suggests that this alternative explanation may be true.(({{pubmed>long:14631060}})) (({{pubmed>long:20377753}})) For example, a 2010 study found that several bacterial taxa in the oral cavity and the gut correlated with plasma cholesterol levels(({{pubmed>long:20937873}})), and another [[http://www.chromatographytoday.com/news/hplc-uhplc-lc-ms/31/breaking_news/high_cholesterol_limits_the_effects_of_human_endotoxemia/15770/|study]] found that high cholesterol protects against endotoxemia.(({{pubmed>long:21711511}}))
  
 Both "good" and "bad" forms of cholesterol play pivotal roles in fighting infection, for example, scavenging endotoxins that are released during destruction of pathogenic bacterial forms. While higher levels of total cholesterol are associated with some forms of cardiovascular disease in some patient populations, a number of statistically significant inverse correlations have been found between total cholesterol and various diseases including chronic heart failure, respiratory and gastrointestinal diseases, and various acute infections.  Both "good" and "bad" forms of cholesterol play pivotal roles in fighting infection, for example, scavenging endotoxins that are released during destruction of pathogenic bacterial forms. While higher levels of total cholesterol are associated with some forms of cardiovascular disease in some patient populations, a number of statistically significant inverse correlations have been found between total cholesterol and various diseases including chronic heart failure, respiratory and gastrointestinal diseases, and various acute infections. 
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 Both "good" and "bad" form of cholesterol play pivotal roles in fighting infection, for example, scavenging endotoxins that are released during destruction of pathogenic bacterial forms. While higher levels of total cholesterol are associated with some forms of cardiovascular disease in some patient populations, a number of statistically significant inverse correlations have been found between total cholesterol and various diseases including chronic heart failure, respiratory and gastrointestinal diseases, and various chronic infections as well.  Both "good" and "bad" form of cholesterol play pivotal roles in fighting infection, for example, scavenging endotoxins that are released during destruction of pathogenic bacterial forms. While higher levels of total cholesterol are associated with some forms of cardiovascular disease in some patient populations, a number of statistically significant inverse correlations have been found between total cholesterol and various diseases including chronic heart failure, respiratory and gastrointestinal diseases, and various chronic infections as well. 
  
-There is also broad evidence that cholesterol does not promote plaque as evidenced by studies that show therapies which directly lower cholesterol may make patients sicker. The article devoted to [[home:othertreatments:antidepressants|statins]] reviews the evidence that statins offer mild protection against disease not through its effect on cholesterol but through their underreported immunomodulatory properties.+There is also broad evidence that cholesterol does not promote plaque as evidenced by studies that show therapies which directly lower cholesterol may make patients sicker. The article devoted to [[home:othertreatments:statins|statins]] reviews the evidence that statins offer mild protection against disease not through its effect on cholesterol but through their underreported immunomodulatory properties.
  
 Some patients on the Marshall Protocol (MP) have reported temporary increases in cholesterol and triglycerides, an observation which is consistent with a heightened immune response.  Some patients on the Marshall Protocol (MP) have reported temporary increases in cholesterol and triglycerides, an observation which is consistent with a heightened immune response. 
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 ===== Statins and other anti-cholesterol drugs    =====  ===== Statins and other anti-cholesterol drugs    ===== 
  
-<mainarticle> [[home:othertreatments:antidepressants|Statins and other anti-cholesterol drugs]]</article>+<mainarticle> [[home:othertreatments:statins|Statins and other anti-cholesterol drugs]]</article>
  
 {{section>:home:othertreatments:statins#statins_and_other_anti-cholesterol_drugs_and_supplements&noheader&firstseconly}} {{section>:home:othertreatments:statins#statins_and_other_anti-cholesterol_drugs_and_supplements&noheader&firstseconly}}
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 </blockquote> </blockquote>
 ===== Notes and comments ===== ===== Notes and comments =====
-TECHEDIT+
  
   * Legacy content   * Legacy content
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 +<blockquote>http://ageing.oxfordjournals.org/content/39/6/674.abstract
 +
 +http://www.lipidsonline.org/news/article.cfm?aid=9907
 +
 +Lipid-lowering treatment to the end? A review of observational studies and RCTs on cholesterol and mortality in 80+-year olds
 +Abstract
 +
 +People aged 80 or older are the fastest growing population in high-income countries. One of the most common causes of death among the elderly is the cardiovascular disease (CVD). Lipid-lowering treatment is common, e.g. one-third of 75–84-year-old Swedes are treated with statins [ 3]. The assumption that hypercholesterolaemia is a risk factor at the highest ages seems to be based on extrapolation from younger adults. A review of observational studies shows a trend where all-cause mortality was highest when total cholesterol (TC) was lowest (‘a reverse J-shaped’ association between TC and all-cause mortality). Low TC (<5.5 mmol/l) is associated with the highest mortality rate in 80+-year olds. No clear optimal level of TC was identified. A review of the few randomised controlled trials including 80+-year olds did not provide evidence of an effect of lipid-lowering treatment on total mortality in 80+-year-old people. There is not sufficient data to recommend anything regarding initiation or continuation of lipid-lowering treatment for the population aged 80+, with known CVD, and it is even possible that statins may increase all-cause mortality in this group of elderly individuals without CVD.</blockquote>
  
 ===== References ===== ===== References =====
home/tests/lipids.txt · Last modified: 09.14.2022 by 127.0.0.1
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