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--- home:tests:liver [10.12.2018] – [Patients experiences] sallieq
+++ home:tests:liver [09.14.2022] (current) – external edit 127.0.0.1
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 ===== Beneficial effects of olmesartan on liver disease =====
-The renin-angiotensin system (RAS) is frequently activated in patients with chronic liver diseases. Angiotensin-II (AT-II) has been suggested to play an important role in the progression of liver fibrogenesis.(({{pubmed>long:11584371}})) (({{pubmed>long:16919500}}))
+The renin-angiotensin system (RAS) is frequently activated in patients with chronic liver diseases. Angiotensin-II (AT-II) has been suggested to play an important role in the progression of liver fibrogenesis.(({{pmid>long:11584371}})) (({{pmid>long:16919500}}))
 Some of the documented protective effects of the angiotension receptor blocker, olmesartan, include the ability to:
-  * **inhibit liver fibrosis and aid liver healing** – Olmesartan medoxomil was given to fibrotic rats. Liver hydroxyproline content, the mRNA expression of collagen alpha1(I) and alpha-smooth muscle actin (alpha-SMA), and plasma levels of transforming growth factor-beta1 (TGF-beta1) were significantly reduced by olmesartan treatment, suggesting that olmesartan improved liver fibrosis.(({{pubmed>long:12871826}})) A second study came to similar conclusion.(({{pubmed>long:19303015}}))
+  * **inhibit liver fibrosis and aid liver healing** – Olmesartan medoxomil was given to fibrotic rats. Liver hydroxyproline content, the mRNA expression of collagen alpha1(I) and alpha-smooth muscle actin (alpha-SMA), and plasma levels of transforming growth factor-beta1 (TGF-beta1) were significantly reduced by olmesartan treatment, suggesting that olmesartan improved liver fibrosis.(({{pmid>long:12871826}})) A second study came to similar conclusion.(({{pmid>long:19303015}}))
-  * **reduce fatty liver** – Fatty liver developed in Zucker fatty rats was ameliorated by olmesartan treatment.(({{pubmed>long: 15082419}})) "Taken in sum," one team concluded, "ARB improves the overproduction and accumulation of TG in the liver associated with insulin resistance, and it does so through mechanisms independent of its hypotensive action."
+  * **reduce fatty liver** – Fatty liver developed in Zucker fatty rats was ameliorated by olmesartan treatment.(({{pmid>long: 15082419}})) "Taken in sum," one team concluded, "ARB improves the overproduction and accumulation of TG in the liver associated with insulin resistance, and it does so through mechanisms independent of its hypotensive action."
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 {{tag>tests}}
+<nodisp>
 ===== Notes and comments =====
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 </blockquote>
-===== References =====
+===== References =====</nodisp>

home/tests/liver.txt · Last modified: 09.14.2022 by 127.0.0.1