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home:diseases:addisons [01.06.2019] – [Notes and comments] sallieq | home:diseases:addisons [01.18.2019] – [Evidence of infectious cause] sallieq | ||
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- | ===== Evidence of infectious cause ===== | + | ===== Delay in diagnosis |
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+ | Addison' | ||
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+ | Addison' | ||
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+ | A LONG FOLLOW-UP STUDY ON 143 PATIENTS.(({{pubmed> | ||
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+ | In addition to the common " | ||
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+ | (({{pubmed> | ||
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===== Recent research ===== | ===== Recent research ===== | ||
- | Even though efficient and safe pharmaceutical preparations for the substitution of endogenous gluco- and mineralocorticoids are established in therapy, the mortality in patients with PAI is still increased and the health-related quality of life (HRQoL) is often reduced. PAI is a rare disease but recent data report an increasing prevalence. In addition to the common " | + | Even though efficient and safe pharmaceutical preparations for the substitution of endogenous gluco- and mineralocorticoids are established in therapy, the mortality in patients with primary adrenal insufficiency (PAI) is still increased and the health-related quality of life (HRQoL) is often reduced. PAI is a rare disease but recent data report an increasing prevalence. In addition to the common " |
Acute adrenal crisis is a life-threatening condition that requires immediate treatment. Standard replacement therapy consists of multiple daily doses of hydrocortisone or cortisone acetate combined with fludrocortisone. Annual follow-up by an endocrinologist is recommended with the focus on optimization of replacement therapy and detection of new autoimmune diseases. | Acute adrenal crisis is a life-threatening condition that requires immediate treatment. Standard replacement therapy consists of multiple daily doses of hydrocortisone or cortisone acetate combined with fludrocortisone. Annual follow-up by an endocrinologist is recommended with the focus on optimization of replacement therapy and detection of new autoimmune diseases. | ||
- | The most common causes of PAI are autoimmune adrenalitis (Addison' | + | The most common causes of PAI are autoimmune adrenalitis (Addison' |
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Main presenting symptoms of Addison' | Main presenting symptoms of Addison' | ||
- | New-onset autoimmune Addison' | + | New-onset autoimmune Addison' |
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+ | The prevalence of the metabolic syndrome in patients with AM was 35.71% after a period of treatment longer than 15 years. (({{pubmed> | ||
===== Patient' | ===== Patient' | ||
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- | Sample PubMed cite(({{pubmed> | + | |