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home:diseases:anorexia_bulimia [02.06.2019] – [Notes and comments] sallieqhome:diseases:anorexia_bulimia [08.12.2019] – [Patient experiences] sallieq
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 ====== Anorexia and bulimia ====== ====== Anorexia and bulimia ======
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-===== Introduction ===== 
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- 
  
 Discussion in The Economist print edition 29 Sep 2005 Discussion in The Economist print edition 29 Sep 2005
 [[http://www.economist.com/displaystory.cfm?story_id=4455455|Molecular self-loathing]] [[http://www.economist.com/displaystory.cfm?story_id=4455455|Molecular self-loathing]]
  
-===== Management =====+===== Evidence of infectious cause ===== 
 + 
 + The intrinsic ability of bacteria to regulate their growth and to maintain their population within the gut suggests that gut bacteria can interfere with molecular pathways controlling energy balance in the host. (({{pubmed>long:27616451}})) 
 + 
 +===== Immune overload =====
  
  
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 [[http://www.eurekalert.org/pub_releases/2009-07/uoc--rpn072109.php|New imaging technology]] at U.Cal. San Diego provides insight into abnormalities in the brain circuitry of patients with anorexia nervosa that may contribute to the puzzling symptoms found in people with the eating disorder. [[http://www.eurekalert.org/pub_releases/2009-07/uoc--rpn072109.php|New imaging technology]] at U.Cal. San Diego provides insight into abnormalities in the brain circuitry of patients with anorexia nervosa that may contribute to the puzzling symptoms found in people with the eating disorder.
 <blockquote>Under Kaye's leadership, the eating disorders treatment program at UC San Diego is developing treatments based on understanding the temperament and personality that drives anorexia, and helping patients to use such traits in constructive, rather then self-defeating ways.</blockquote>  <blockquote>Under Kaye's leadership, the eating disorders treatment program at UC San Diego is developing treatments based on understanding the temperament and personality that drives anorexia, and helping patients to use such traits in constructive, rather then self-defeating ways.</blockquote> 
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 +
  
  
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-===== Evidence of infectious cause ===== 
  
- The intrinsic ability of bacteria to regulate their growth and to maintain their population within the gut suggests that gut bacteria can interfere with molecular pathways controlling energy balance in the host. (({{pubmed>long:27616451}})) 
  
-===== Further Research  ===== 
- 
-We found significantly altered correlations between alpha-MSH autoAb levels and the total Eating Disorder Inventory-2 score, as well as most of its subscale dimensions in AN and BN patients vs. controls. Remarkably, these correlations were opposite in AN vs. BN patients. In contrast, levels of autoAbs reacting with adrenocorticotropic hormone, OT, or VP had only few altered correlations with the Eating Disorder Inventory-2 subscale dimensions in AN and BN patients. Thus, our data reveal that core psychobehavioral abnormalities characteristic for eating disorders correlate with the levels of autoAbs against alpha-MSH, suggesting that AN and BN may be associated with autoAb-mediated dysfunctions of primarily the melanocortin system.  //Fetissov SO, et al//(({{pubmed>long:16195379}})) 
- 
-Hypovolemia-induced obesity and diabetes. (({{pubmed>long:19709692}})) Hypovolemia is a diminished volume of circulating blood in the body. Therefore is it obviously important to guard against dehydration. 
- 
-Imaging studies reveal[[http://www.eurekalert.org/pub_releases/2009-07/uoc--rpn072109.php|Differences]] in the brain circuitry of patients with anorexia nervosa (commonly known as anorexia) that may contribute to the puzzling symptoms found in people with the eating disorder.  (({{pubmed>long:21243469}})) 
- 
- 
-[[http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007125|Monitoring Bacterial Community]] of Human Gut Microbiota Reveals an Increase in Lactobacillus in Obese Patients and Methanogens in Anorexic Patients (({{pubmed>long:19774074}}))  
- 
-Famine may affect the microbiome in a lasting way(({{pubmed>long:14696131}})) 
-[[http://www.ncbi.nlm.nih.gov/pubmed/14696131|psychological traits in eating disorders]] 
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-in New Insights in Anorexia Nervosa (({{pubmed>long:27445651}}))  
-P. Gorwood, J. Epelbaum and colleagues assemble seven possible models, each accompanied by illustrative figures. 
  
  
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 So that is it. I am starting to feel normal again. I even have less of the nerve issues in my hands now. I didn't think things like that would ever go back to normal. But I can feel them normalizing. The word for me is beginning to be…NORMAL.  4.5 years on the Marshall, (was on one antibiotic protocol or another since July of 2005).  So that is it. I am starting to feel normal again. I even have less of the nerve issues in my hands now. I didn't think things like that would ever go back to normal. But I can feel them normalizing. The word for me is beginning to be…NORMAL.  4.5 years on the Marshall, (was on one antibiotic protocol or another since July of 2005). 
 +
 +===== Further Research  =====
 +
 +We found significantly altered correlations between alpha-MSH autoAb levels and the total Eating Disorder Inventory-2 score, as well as most of its subscale dimensions in AN and BN patients vs. controls. Remarkably, these correlations were opposite in AN vs. BN patients. In contrast, levels of autoAbs reacting with adrenocorticotropic hormone, OT, or VP had only few altered correlations with the Eating Disorder Inventory-2 subscale dimensions in AN and BN patients. Thus, our data reveal that core psychobehavioral abnormalities characteristic for eating disorders correlate with the levels of autoAbs against alpha-MSH, suggesting that AN and BN may be associated with autoAb-mediated dysfunctions of primarily the melanocortin system.  //Fetissov SO, et al//(({{pubmed>long:16195379}}))
 +
 +Hypovolemia-induced obesity and diabetes. (({{pubmed>long:19709692}})) Hypovolemia is a diminished volume of circulating blood in the body. Therefore is it obviously important to guard against dehydration.
 +
 +Imaging studies reveal[[http://www.eurekalert.org/pub_releases/2009-07/uoc--rpn072109.php|Differences]] in the brain circuitry of patients with anorexia nervosa (commonly known as anorexia) that may contribute to the puzzling symptoms found in people with the eating disorder.  (({{pubmed>long:21243469}}))
 +
 +
 +[[http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007125|Monitoring Bacterial Community]] of Human Gut Microbiota Reveals an Increase in Lactobacillus in Obese Patients and Methanogens in Anorexic Patients (({{pubmed>long:19774074}})) 
 +
 +Famine may affect the microbiome in a lasting way(({{pubmed>long:14696131}}))
 +[[http://www.ncbi.nlm.nih.gov/pubmed/14696131|psychological traits in eating disorders]]
 +
 +in New Insights in Anorexia Nervosa (({{pubmed>long:27445651}})) 
 +P. Gorwood, J. Epelbaum and colleagues assemble seven possible models, each accompanied by illustrative figures.
  
  
home/diseases/anorexia_bulimia.txt · Last modified: 09.14.2022 by 127.0.0.1
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