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home:diseases:depression [02.18.2019] – [Patient experience] sallieqhome:diseases:depression [10.10.2019] – [Introduction] sallieq
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 [[https://onlinelibrary.wiley.com/doi/full/10.1111/nmo.12198|Impact of microbiota on brain function]] [[https://onlinelibrary.wiley.com/doi/full/10.1111/nmo.12198|Impact of microbiota on brain function]]
  
 +2019 There is strong epidemiological evidence that poor diet is associated with depression. The reverse has also been shown, namely that eating a healthy diet rich in fruit, vegetables, fish and lean meat, is associated with reduced [[https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0222768#pone.0222768.ref012|risk of depression]].(({{pubmed>long:88888888}})) 
 ===== Virtues of depression ===== ===== Virtues of depression =====
  
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 [[https://www.bbc.com/news/health-37166293|many don't respond to existing therapies and so some scientists are now exploring a new frontier - whether the immune system could be causing depression.]] [[https://www.bbc.com/news/health-37166293|many don't respond to existing therapies and so some scientists are now exploring a new frontier - whether the immune system could be causing depression.]]
  
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 +[[http://www.jneuropsychiatry.org/peer-review/depression-and-inflammation-disentangling-a-clear-yet-complex-and-multifaceted-link.html|depression and inflammation seem closely connected. Specifically that patients with inflammatory diseases are more likely to have MDD,  a large number of people with major depression show inflammatory biomarkers, and patients treated with cytokines are at increased risk of developing depression. Also inflammatory mediators have been found to alter glutamate and monoamine neurotransmission, glucocorticoid receptor resistance and hippocampal neurogenesis. Also, inflammation is able to alter brain signalling patterns, to affect cognition.]]
  
  
 +The 'cytokine hypothesis of depression' implies that proinflammatory cytokines, acting as neuromodulators, represent the key factor in the (central) mediation of the behavioural, neuroendocrine and neurochemical features of depressive disorders. This view is supported by various findings. Several medical illnesses, which are characterised by chronic inflammatory responses, e.g. rheumatoid arthritis, have been reported to be accompanied by depression. (({{pubmed>long:    15694227}}))
  
  
home/diseases/depression.txt · Last modified: 09.14.2022 by 127.0.0.1
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