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home:diseases:depression [06.28.2019] – [Recent research] sallieqhome:diseases:depression [04.09.2020] – [Immune signaling] sallieq
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 [[https://onlinelibrary.wiley.com/doi/full/10.1111/nmo.12198|Impact of microbiota on brain function]] [[https://onlinelibrary.wiley.com/doi/full/10.1111/nmo.12198|Impact of microbiota on brain function]]
  
 +2019 There is strong epidemiological evidence that poor diet is associated with depression. The reverse has also been shown, namely that eating a healthy diet rich in fruit, vegetables, fish and lean meat, is associated with reduced [[https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0222768#pone.0222768.ref012|risk of depression]].(({{pubmed>long:88888888}})) 
 ===== Virtues of depression ===== ===== Virtues of depression =====
  
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 In the research field of psychoneuroimmunology, accumulating evidence has indicated the existence of reciprocal communication pathways between nervous, endocrine and immune systems. In this respect, there has been increasing interest in the putative involvement of the immune system in psychiatric disorders. Cytokines and major depression (({{pubmed>long:15694227}}))  In the research field of psychoneuroimmunology, accumulating evidence has indicated the existence of reciprocal communication pathways between nervous, endocrine and immune systems. In this respect, there has been increasing interest in the putative involvement of the immune system in psychiatric disorders. Cytokines and major depression (({{pubmed>long:15694227}})) 
 +
 +==== Immune suppression ====
  
 ===== Immune signaling ===== ===== Immune signaling =====
 +
  
 A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells (({{pubmed>long:16223770}}))   A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells (({{pubmed>long:16223770}}))  
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 +The 'cytokine hypothesis of depression' implies that proinflammatory cytokines, acting as neuromodulators, represent the key factor in the (central) mediation of the behavioural, neuroendocrine and neurochemical features of depressive disorders. This view is supported by various findings. Several medical illnesses, which are characterised by chronic inflammatory responses, e.g. rheumatoid arthritis, have been reported to be accompanied by depression. (({{pubmed>long:    15694227}}))
  
  
home/diseases/depression.txt · Last modified: 09.14.2022 by 127.0.0.1
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