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home:diseases:ibd [01.18.2019] – [Serum levels of 'vitamin' D] sallieqhome:diseases:ibd [02.17.2019] – [Inflammatory bowel disease (Crohn's disease and ulcerative colitis)] sallieq
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 +<relatedarticle> [[home:diseases:ibs|IBS]] </article>
 ===== Introduction ===== ===== Introduction =====
  
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     * //Pseudomonas maltophilia// (({{pubmed>long:780185}}))     * //Pseudomonas maltophilia// (({{pubmed>long:780185}}))
  
-De Hertogh //et al// provide a [[http://www.wjgnet.com/1007-9327/14/845.asp|thorough review]] of the "unidentified persistent pathogen" theory, stating: +De Hertogh //et al// provide a thorough review of the "unidentified persistent pathogen" theory, stating: 
  
 <blockquote>Various environmental factors may play a role in the development of CD [Crohn's Disease], but microbes are most consistently implied. This theory is based on epidemiological, clinicopathological, genetic and experimental evidence. (({{pubmed>long:18240341}}))</blockquote> <blockquote>Various environmental factors may play a role in the development of CD [Crohn's Disease], but microbes are most consistently implied. This theory is based on epidemiological, clinicopathological, genetic and experimental evidence. (({{pubmed>long:18240341}}))</blockquote>
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 "It is increasingly apparent that bacteria are playing a role in healthy development, and need to be properly managed by the mucosal immune system to avoid inflammatory diseases" Gewirtz explained. (({{pubmed>long:22863420}})) </blockquote> "It is increasingly apparent that bacteria are playing a role in healthy development, and need to be properly managed by the mucosal immune system to avoid inflammatory diseases" Gewirtz explained. (({{pubmed>long:22863420}})) </blockquote>
  
-===== Recent research =====+===== Research =====
  
 Development, validation and implementation of an in vitro model for the study of metabolic and immune function in normal and inflamed human colonic epithelium.  (({{pubmed>long:25557335}}))  Development, validation and implementation of an in vitro model for the study of metabolic and immune function in normal and inflamed human colonic epithelium.  (({{pubmed>long:25557335}})) 
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 +'Western'-style diets, high in fat/sugar, low in fibre, decrease beneficial Firmicutes that metabolise dietary plant-derived polysaccharides to SCFAs and increase mucosa-associated Proteobacteria (including enteric pathogens).   (({{pubmed>long:26011307}})) 
 +
 +[[https://www.sciencemag.org/news/2018/11/do-gut-bacteria-make-second-home-our-brains|Roberts doesn’t know how these bacteria could have gotten into the brain. They may have crossed from blood vessels, traveling up nerves from the gut, or even come in through the nose]]
 +  
  
 =====  Patient interviews  ===== =====  Patient interviews  =====
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 {{tag>disease }} {{tag>disease }}
 +
  
  
  
 ===== Notes and comments ===== ===== Notes and comments =====
-(({{pubmed>long:99999999}})) + 
 +(({{pubmed>long:000}}))  
 + 
 broken link http://mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD007735/frame.html broken link http://mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD007735/frame.html
 +another, maybe [[http://www.wjgnet.com/1007-9327/14/845.asp|thorough review]] 
  
 <DiseaseHierarchy> <DiseaseHierarchy>
home/diseases/ibd.txt · Last modified: 09.14.2022 by 127.0.0.1
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