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home:diseases:kidney_disease [02.17.2019] – [Kidney disease] sallieq | home:diseases:kidney_disease [02.19.2019] – [Patients experiences] sallieq | ||
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====== Kidney disease ====== | ====== Kidney disease ====== | ||
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- | Am J Kidney Dis. 2009 Apr; | + | Calcium-alkali syndrome due to vitamin D administration and magnesium oxide administration.(({{pubmed> |
- | Calcium-alkali syndrome due to vitamin D administration and magnesium oxide administration. | + | |
- | Hanada S, Iwamoto M, Kobayashi N, Ando R, Sasaki S. | + | |
- | Department of Nephrology, Musashino Red Cross Hospital, Tokyo Medical and Dental University, Tokyo, Japan. s-hanada@umin.ac.jp | + | |
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Got Calcium? Welcome to the Calcium-Alkali Syndrome. | Got Calcium? Welcome to the Calcium-Alkali Syndrome. | ||
- | Patel AM, Goldfarb S | + | |
- | J Am Soc Nephrol Apr 2010; | + | |
- | Download citation | + | |
- | Affiliation | + | |
- | Renal-Electrolyte and Hypertension Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, | + | |
Abstract | Abstract | ||
We recommend changing the name of the milk-alkali syndrome to the calcium-alkali syndrome, because the new terminology better reflects the shifting epidemiology and understanding of this disorder. The calcium-alkali syndrome is now the third most common cause of hospital admission for hypercalcemia, | We recommend changing the name of the milk-alkali syndrome to the calcium-alkali syndrome, because the new terminology better reflects the shifting epidemiology and understanding of this disorder. The calcium-alkali syndrome is now the third most common cause of hospital admission for hypercalcemia, | ||
- | The incidence of the calcium-alkali syndrome is growing in large part as a result of the widespread use of over-the-counter calcium and vitamin D supplements.Advertising for treatment or prevention of osteoporosis has long encouraged this use. Intricate mechanisms mediating the calcium-alkali syndrome depend on interplay among intestine, kidney, and bone. New insights regarding its pathogenesis focus on the key role of calcium-sensing receptors and TRPV5 channels in the modulation of renal calcium excretion. Restoring extracellular blood volume, increasing GFR and calcium excretion, and discontinuing calcium supplementation provide best treatment. | + | The incidence of the calcium-alkali syndrome is growing in large part as a result of the widespread use of over-the-counter calcium and vitamin D supplements. Advertising for treatment or prevention of osteoporosis has long encouraged this use. |
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+ | Intricate mechanisms mediating the calcium-alkali syndrome depend on interplay among intestine, kidney, and bone. New insights regarding its pathogenesis focus on the key role of calcium-sensing receptors and TRPV5 channels in the modulation of renal calcium excretion. | ||
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+ | Restoring extracellular blood volume, increasing GFR and calcium excretion, and discontinuing calcium supplementation provide best treatment. | ||
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