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home:diseases:obesity [02.08.2019] – [Recent research] sallieq | home:diseases:obesity [02.08.2019] – [Recent research] sallieq | ||
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- | ==== Recent research | + | ==== Research |
Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance. | Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance. | ||
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Here, we report that adenosine level in the cerebrospinal fluid, and hypothalamic expression of A1R, are increased in the diet-induced obesity (DIO) mouse. We find that mice with overexpression of A1R in the neurons of paraventricular nucleus (PVN) of the hypothalamus are hyperphagic, | Here, we report that adenosine level in the cerebrospinal fluid, and hypothalamic expression of A1R, are increased in the diet-induced obesity (DIO) mouse. We find that mice with overexpression of A1R in the neurons of paraventricular nucleus (PVN) of the hypothalamus are hyperphagic, | ||
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+ | Higher zonulin levels are associated with higher waist circumference, | ||
==== Childhood ==== | ==== Childhood ==== | ||