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home:diseases:osteoarthritis [01.05.2019] – [Manangement] sallieq | home:diseases:osteoarthritis [01.11.2019] – [Introduction] sallieq | ||
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+ | [[https:// | ||
- | + | Usefulness of broad-range PCR for the diagnosis of osteoarticular infections.(({{pubmed> | |
===== Evidence of infectious cause ===== | ===== Evidence of infectious cause ===== | ||
- | Since studies are now showing that tetracycline can slow down the OA process, this suggests that this process is caused | + | Since studies are now showing that tetracycline can slow down the OA process, this suggests that this process is impacted |
- | The almost universal use of methotrexate and the rapid development of potent biologic agents have eclipsed the potential usage of TETs for RA. Ironically, it is in osteoarthritis, | + | < |
- | Sample PubMed cite(({{pubmed> | + | |
- | ===== s249 ===== | + | ===== Accepted knowledge |
[[http:// | [[http:// | ||
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-common x-ray findings of osteoarthritis include loss of joint cartilage, narrowing of the joint space between adjacent bones, and bone spur formation. | -common x-ray findings of osteoarthritis include loss of joint cartilage, narrowing of the joint space between adjacent bones, and bone spur formation. | ||
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+ | ==== MP comment ==== | ||
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I am having more and more difficulty accepting any disease or symptom are merely being part of the ' | I am having more and more difficulty accepting any disease or symptom are merely being part of the ' | ||
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Altogether, our data show that tetracyclines have no inhibitory potential on any proteoglycanolytic activities within mild or moderately affected human OA cartilage at therapeutic achievable plasma levels. | Altogether, our data show that tetracyclines have no inhibitory potential on any proteoglycanolytic activities within mild or moderately affected human OA cartilage at therapeutic achievable plasma levels. | ||
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+ | Biomarkers of early stage osteoarthritis, | ||
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+ | After adjusting for all the covariates, the relative odds (95% confidence interval) of developing definite knee OA per increment of 1 SD (20.7 ng/mL) in winter season 25(OH)D was 1.57 (1.10-2.27), | ||
+ | CONCLUSION: The results do not support the hypothesis that a low level of serum 25(OH)D contributes to the development of OA. (({{pubmed> | ||
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- | {{tag> | + | {{tag> |
- | < | ||