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home:diseases:osteoarthritis [01.05.2019] – [Research] sallieqhome:diseases:osteoarthritis [01.11.2019] – [Research] sallieq
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 Biomarkers of early stage osteoarthritis, rheumatoid arthritis and musculoskeletal health.  <blockquote>We detected CP in the plasma of healthy subjects and surprisingly found that CP was increased in both patients with eOA and eRA whereas anti-CCP antibodies were predominantly present in eRA. A 4-class diagnostic algorithm combining plasma/serum CP, anti-CCP antibody and hydroxyproline applied to a cohort gave specific and sensitive detection and discrimination of eOA, eRA, other non-RA inflammatory joint diseases and good skeletal health.(({{pubmed>long:25788417}}))</blockquote> Biomarkers of early stage osteoarthritis, rheumatoid arthritis and musculoskeletal health.  <blockquote>We detected CP in the plasma of healthy subjects and surprisingly found that CP was increased in both patients with eOA and eRA whereas anti-CCP antibodies were predominantly present in eRA. A 4-class diagnostic algorithm combining plasma/serum CP, anti-CCP antibody and hydroxyproline applied to a cohort gave specific and sensitive detection and discrimination of eOA, eRA, other non-RA inflammatory joint diseases and good skeletal health.(({{pubmed>long:25788417}}))</blockquote>
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 +After adjusting for all the covariates, the relative odds (95% confidence interval) of developing definite knee OA per increment of 1 SD (20.7 ng/mL) in winter season 25(OH)D was 1.57 (1.10-2.27), whereas for summer season sera the corresponding rate was 0.53 (0.28-1.00).
 +CONCLUSION: The results do not support the hypothesis that a low level of serum 25(OH)D contributes to the development of OA. (({{pubmed>long:22043944}})) 
          
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home/diseases/osteoarthritis.txt · Last modified: 09.14.2022 by 127.0.0.1
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