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home:diseases:osteoarthritis [01.11.2019] – [Research] sallieq | home:diseases:osteoarthritis [09.14.2022] (current) – external edit 127.0.0.1 | ||
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+ | Usefulness of broad-range PCR for the diagnosis of osteoarticular infections.(({{pmid> | ||
===== Evidence of infectious cause ===== | ===== Evidence of infectious cause ===== | ||
Since studies are now showing that tetracycline can slow down the OA process, this suggests that this process is impacted by bacteria. I suspect that lost cartilage will not be replaced but that eliminating CWD bacteria might halt the degenerative process. | Since studies are now showing that tetracycline can slow down the OA process, this suggests that this process is impacted by bacteria. I suspect that lost cartilage will not be replaced but that eliminating CWD bacteria might halt the degenerative process. | ||
- | < | + | < |
- | Sample PubMed cite(({{pubmed> | ||
===== Accepted knowledge ===== | ===== Accepted knowledge ===== | ||
- | [[http:// | + | [[https:// |
< | < | ||
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===== Management ===== | ===== Management ===== | ||
- | Is aquatic exercise more effective than land-based exercise for knee osteoarthritis? | + | Is aquatic exercise more effective than land-based exercise for knee osteoarthritis? |
===== Research ===== | ===== Research ===== | ||
- | Why does hyaline cartilage fail to repair? | + | Why does hyaline cartilage fail to repair? |
- | a comprehensive review on recent literature describing signal pathways in the hypertrophy of MSCs-derived in vitro differentiated chondrocytes and chondrocytes, | + | a comprehensive review on recent literature describing signal pathways in the hypertrophy of MSCs-derived in vitro differentiated chondrocytes and chondrocytes, |
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- | Cytokines such as IL-1 and TNF-alpha produced by activated synoviocytes, | + | Cytokines such as IL-1 and TNF-alpha produced by activated synoviocytes, |
- | Altogether, our data show that tetracyclines have no inhibitory potential on any proteoglycanolytic activities within mild or moderately affected human OA cartilage at therapeutic achievable plasma levels. | + | Altogether, our data show that tetracyclines have no inhibitory potential on any proteoglycanolytic activities within mild or moderately affected human OA cartilage at therapeutic achievable plasma levels. |
- | Biomarkers of early stage osteoarthritis, | + | Biomarkers of early stage osteoarthritis, |
After adjusting for all the covariates, the relative odds (95% confidence interval) of developing definite knee OA per increment of 1 SD (20.7 ng/mL) in winter season 25(OH)D was 1.57 (1.10-2.27), | After adjusting for all the covariates, the relative odds (95% confidence interval) of developing definite knee OA per increment of 1 SD (20.7 ng/mL) in winter season 25(OH)D was 1.57 (1.10-2.27), | ||
- | CONCLUSION: The results do not support the hypothesis that a low level of serum 25(OH)D contributes to the development of OA. (({{pubmed> | + | CONCLUSION: The results do not support the hypothesis that a low level of serum 25(OH)D contributes to the development of OA. (({{pmid> |
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{{tag> | {{tag> | ||
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+ | < | ||
===== Notes and comments ===== | ===== Notes and comments ===== | ||
+ | Somewhere I think I have seen the idea that microbes multipy with ease in damged tissu... if only i knew where (sigh) --- //Sallie Q 02.17.2019// | ||
+ | |||
+ | |||
+ | //broken link// | ||
broken promise ?? | broken promise ?? | ||
The Promise of a Tetracycline Antibiotic for Treating Osteoarthritis | The Promise of a Tetracycline Antibiotic for Treating Osteoarthritis | ||
- | [[http:// | + | [[https:// |
< | < | ||
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* legacy content | * legacy content | ||
- | * http:// | + | * https:// |
+ | https:// | ||
- | http:// | ||
+ | ===== References =====</ | ||
- | ===== References ===== |