This shows you the differences between two versions of the page.
Both sides previous revisionPrevious revisionNext revision | Previous revision | ||
home:food:folic [01.30.2018] – [Epidemiological evidence] sallieq | home:food:folic [09.14.2022] (current) – external edit 127.0.0.1 | ||
---|---|---|---|
Line 19: | Line 19: | ||
- | Folate naturally in foods is [[http:// | + | Folate naturally in foods is [[https:// |
* 1 µg of dietary folate equivalent = 0.6 µg of folic acid from fortified food, or | * 1 µg of dietary folate equivalent = 0.6 µg of folic acid from fortified food, or | ||
* 1 µg of food folate = 0.5 µg of a supplement taken on an empty stomach | * 1 µg of food folate = 0.5 µg of a supplement taken on an empty stomach | ||
Line 28: | Line 28: | ||
Folic acid is converted by the body into DHFR (DiHydro-Folate Reductase), which can be used by parasitic bacteria to form the nucleic acids, which are at the basis of their survival and reproductive cycles. | Folic acid is converted by the body into DHFR (DiHydro-Folate Reductase), which can be used by parasitic bacteria to form the nucleic acids, which are at the basis of their survival and reproductive cycles. | ||
- | So important is folic acid to the growth of bacteria that many therapies for infections slow disease progress by blocking activity of folic acid. A conventional treatment for sarcoidosis confirms that folic acid does indeed affect the activity of L-form bacteria. Some patients with sarcoidosis are prescribed [[http:// | + | So important is folic acid to the growth of bacteria that many therapies for infections slow disease progress by blocking activity of folic acid. A conventional treatment for sarcoidosis confirms that folic acid does indeed affect the activity of L-form bacteria. Some patients with sarcoidosis are prescribed [[https:// |
< | < | ||
Line 39: | Line 39: | ||
//**Trevor Marshall, PhD**//</ | //**Trevor Marshall, PhD**//</ | ||
+ | |||
+ | Folic acid as a supplement may also mask the symptoms of severe vitamin B12 deficiency. | ||
===== FDA supplementation policy ===== | ===== FDA supplementation policy ===== | ||
Line 48: | Line 50: | ||
===== Clinical evidence ===== | ===== Clinical evidence ===== | ||
- | A 2009 combined analysis and extended follow-up of participants from two randomized, double-blind, | + | A 2009 combined analysis and extended follow-up of participants from two randomized, double-blind, |
Line 62: | Line 64: | ||
fortification (1992–1996) and after (2001–2004) — and found a significant | fortification (1992–1996) and after (2001–2004) — and found a significant | ||
increase in reported cases of colon cancer. The increase was 162% in people | increase in reported cases of colon cancer. The increase was 162% in people | ||
- | 45 to 64 years and 190% in people 65 to 79 years.(({{pubmed> | + | 45 to 64 years and 190% in people 65 to 79 years.(({{pmid> |
A pair of commentaries appearing in the November 2007 issue of //Nutrition Reviews// argue that folic acid benefits some and harms others. | A pair of commentaries appearing in the November 2007 issue of //Nutrition Reviews// argue that folic acid benefits some and harms others. | ||
- | Dr. Solomons, author of one of the review commentaries, | + | Dr. Solomons, author of one of the review commentaries, |
- | Dr. Young-In Kim authored the second commentary: “Folic Acid Fortification and Supplementation—Good for Some but Not So Good for Others.”(({{pubmed> | + | Dr. Young-In Kim authored the second commentary: “Folic Acid Fortification and Supplementation—Good for Some but Not So Good for Others.”(({{pmid> |
- | A 2010 study by House //et al.// has shown substantial adverse outcomes associated with high-dose B vitamins in patients with advanced diabetic nephropathy.(({{pubmed> | + | A 2010 study by House //et al.// has shown substantial adverse outcomes associated with high-dose B vitamins in patients with advanced diabetic nephropathy.(({{pmid> |
The conclusions expressed in these studies and reviews are consistent with the contention that supplemental folic acid is most harmful for people who are older and presumably have higher microbial loads. | The conclusions expressed in these studies and reviews are consistent with the contention that supplemental folic acid is most harmful for people who are older and presumably have higher microbial loads. | ||
- | ===== Natural sources of folic acid ===== | + | ===== Natural sources of folate |
Dark leafy greens, citrus, beans and lentils, avocado | Dark leafy greens, citrus, beans and lentils, avocado | ||
- | [[https:// | + | [[https:// |
===== Read more ===== | ===== Read more ===== | ||
- | * [[http:// | + | * [[https:// |
- | * [[http:// | + | * [[https:// |
- | {{tag> | + | {{tag>Food_and_drink |
+ | < | ||
===== Notes and comments ===== | ===== Notes and comments ===== | ||
- | was broke [[http:// | + | was broke [[https:// |
* Legacy content | * Legacy content | ||
- | * http:// | + | * https:// |
- | * http:// | + | * https:// |
* | * | ||
- | [[http:// | + | [[https:// |
+ | |||
+ | ===== References =====</ | ||
- | ===== References ===== |