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--- home:lifestyle:light:skin_protection [11.05.2010] – external 127.0.0.1
+++ home:lifestyle:light:skin_protection [04.09.2011] – [Notes and comments] paulalbert
@@ Line 13: / Line 13: @@
 The only sunscreen ingredients which appear to offer a significant level of protection from vitamin D production and sun flare symptoms in Th1 patients are zinc oxide, Helioplex, and titanium dioxide.
-Joyce Waterhouse, PhD has produced [[http://www.marshallprotocol.com/view_topic.php?id=2957&forum_id=32&jump_to=140087#p140087|a review]] of the various types of sunscreen. A summary of that review is reproduced below.
+Joyce Waterhouse, PhD has produced [[http://marshallprotocol.com/view_topic.php?id=14078|a review]] of the various types of sunscreen. A summary of that review is reproduced below.
 ==== Zinc oxide ====
@@ Line 24: / Line 24: @@
 ==== Ketoconazole cream ====
-<mainarticle> [[home:othertreatments:antidepressants|Antifungal agents]] </article>
+<mainarticle> [[home:othertreatments:antifungals|Antifungal agents]] </article>
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 ===== Notes and comments =====
 EDIT
+<blockquote>Paul,
+I was thinking you should probably add a stronger statement to the KB  http://mpkb.org/home/lifestyle/light/skin_protection#zinc_oxide  based on what Trevor said.
+-- basically that we now strongly discourage the use of ketonconazole due to its effects on the P450 enzyme system as well as other effects.
+Joyce
+***
+Hi Trevor,
+I realized due to being too busy I had not finished with this issue.  I hadn't been thinking about it until Joyful brought the recent sunscreen discussion to my attention.
+Were discussing the sunscreen threads that I posted in the moderators forum and was about to put in a section where people could see them back in mid November.
+Your comments are below and in response to them:
+I added a statement about ketoconazole cream and the P450 system.
+I replaced the statement about 400 IU D that you objected to with this:
+The symptoms I experienced were identical to what I got from increased IP due to antibiotics.
+So, if that is alright, I will move these several posts to a forum where everyone can see them, since now, the sunscreen overview is mentioned in the kb but the link doesn't work due to it being in an archived forum.
+Joyful, which thread did you think these should go into?  I thought that it should be one everyone could see?
+Joyce
+***
+Well, if you put my disclaimer about ketoconazole right at the beginning of where you start talking about it then I think people are more likely to see it. And add the interference with the key P450 enzymes too. Remember that ketoconazole was banned from internal use after it was found to be toxic. Incidentally, I also have reservations about zinc, you may recall.
+I am not trying to 'buy an argument' but just making sure we document things exactly correctly.
+DeLuca did not find quantities of 25-D being expressed. He most certainly would have quoted Holick if he had found production. Do you want to hang our science on a 1980 Holick paper? To be honest, I haven't had time to re-read either paper - working on abstracts for two conferences at the moment. Tomorrow may be a better time for me.
+..Trevor..
+***
+At 04:39 PM 11/15/2010, Jcwat101@aol.com wrote:
+Trevor,
+I am shortly planning to post what I have just posted in the moderator thread in the General Discussion thread.
+Joyful and Paul and I agreed this was probably the best way to handle the situation with that thread I had started and linking to it in the KB.
+Then, we will link to these posts in the KB.  One of the posts has a link to the discussion thread that I started where people share experiences.
+I had to repost since we were linking to the sunscreen overview in the KB but it had become inaccessible due to the archiving.
+If you don't object, I'll start posting it in the public area this evening and work out with Paul what articles in the KB will link to which posts.
+Let me know if you have any comments or suggestions.
+Joyce
+</blockquote>
   *Legacy content
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 I have about 4 of these misters and everyone steals them from me. I don’t sweat so it really helps to apply a thin layer of mist to my face or chest and use a small personal fan to cool down for those moments when you are really overheating and just need some relief.  It is small and works on a pump action. I found mine at Wal-Mart.
+Hope this gives you some ideas.
+Nelda
@@ Line 183: / Line 249: @@
-Hope this gives you some ideas.
-Nelda
+<blockquote>http://pubs.acs.org/doi/pdf/10.1021/bi101488p
+I previously computed that Ketoconazole was a high-affinity VDR antagonist, but it seems it also has direct affinity for key enzymes in the D metabolism.
+DeLuca's group wrote the paper linked above, so it is focused on the past, with the first sentences of the introduction being boiler-plate peer-reviewer-aggrandizement, but there is a lot of interesting stuff in the paper, especially in the Discussion.
+Bottom line is that we want to cohort to understand why Ketoconozole is (generally) palliative, and why it was banned from internal use some years ago. In short, it is dangerous to life.
+Enjoy (and thanks for the link, Ragnar)
+..Trevor..</blockquote>
+<blockquote>From: jcwat101Date: 2011-02-21 11:06:19
+Reply: http://marshallprotocol.com/reply.php?topic_id=13718
+The two studies Trevor cited regarding sunscreen did not use zinc oxide but the synthetic chemical sunscreens.
+I find that zinc oxide at high concentrations (18-25 %) does work for me if I'm not outside a long time.
+But it only blocks 90% or so of the sun's effects.
+If you are outside more than two or three hours, it becomes less effective.  If you are out 5 or 6 it is almost like you didn't wear it because of the % of the light that gets past the sunscreen.
+I also have evidence from my own experience that the zinc oxide is not absorbed significantly, since if I don't wash it off, it continues to work for days.  Yet briefly washing one's hands for instance means the effect is gone.
+This is unlike the synthetic chemical sunscreens that break down and/or are absorbed within a couple hours of putting them on.
+This supports various studies various laboratory studies of zinc oxide.  I know Trevor is skeptical about the absorption, but since my experience agrees with the studies, I tend to think they are correct.
+Joyce Waterhouse
+See  http://marshallprotocol.com/forum11/13724  for discussion of sun exposure and sunscreens etc...
+From: Dr Trevor Marshall
+Date: 2011-02-21 11:40:42
+Reply: http://marshallprotocol.com/reply.php?topic_id=13718
+Joyce is correct, sunscreens are still a grey area where there is a paucity of real data :)
+</blockquote>
 ===== References =====

home/lifestyle/light/skin_protection.txt · Last modified: 09.14.2022 by 127.0.0.1