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home:othertreatments:efas [06.29.2010] paulalberthome:othertreatments:efas [06.29.2010] paulalbert
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 Greater consumption of omega 3's has been shown to reduce inflammation and immune activity.(({{pubmed>long:19359242}})) Greater consumption of omega 3's has been shown to reduce inflammation and immune activity.(({{pubmed>long:19359242}}))
  
-  * **Mice given omega‐3's are more susceptible to pulmonary tuberculosis** – Bonilla //et al.// showed that  endogenous production of omega-3's in mice increases their susceptibility to tuberculosis, which they explained by noting the corresponding diminished activation and antimycobacterial responses in cells. The researchers concluded, "These data suggest that n‐3 PUFA–supplemented [dietary omega‐3 fatty acids] diets might have a detrimental effect on immunity to //M. tuberculosis// and raise concerns regarding the safety of omega‐3 dietary supplementation in humans."(({{pubmed>long:20053136}})) 
   * **Omega 3's contain components which suppress TNF-alpha** – Cytokines are regulatory proteins, such as TNF-alpha, that are released by cells of the immune system and act as intercellular mediators in the generation of an immune response. The omega 3 fatty acids, for example, contain several components which may interfere with the activity of TNF-alpha and other important cytokines.    * **Omega 3's contain components which suppress TNF-alpha** – Cytokines are regulatory proteins, such as TNF-alpha, that are released by cells of the immune system and act as intercellular mediators in the generation of an immune response. The omega 3 fatty acids, for example, contain several components which may interfere with the activity of TNF-alpha and other important cytokines. 
  
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 //**M. Bouwens**// (({{pubmed>long:19515734}}))</blockquote> //**M. Bouwens**// (({{pubmed>long:19515734}}))</blockquote>
 +===== Omega 3 fatty acids may cause disease =====
  
 +  * **Mice given omega‐3's are more susceptible to pulmonary tuberculosis** – Bonilla //et al.// showed that  transgenic mice engineered to produce omega-3's endogenously (internally) increased their susceptibility to tuberculosis, which they explained by noting the corresponding reduction in antimycobacterial responses in cells. The researchers concluded, "These data suggest that n‐3 PUFA–supplemented [dietary omega‐3 fatty acids] diets might have a detrimental effect on immunity to //M. tuberculosis// and raise concerns regarding the safety of omega‐3 dietary supplementation in humans."(({{pubmed>long:20053136}}))
    
  
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