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--- home:othertreatments:efas [06.29.2010] – paulalbert
+++ home:othertreatments:efas [09.04.2010] – paulalbert
@@ Line 44: / Line 44: @@
 //**M. Bouwens**// (({{pubmed>long:19515734}}))</blockquote>
+  * **EPA and DHA switch off a key receptor responsible for innate immunity in fat cells.**  Olefsky and colleagues identified a key receptor on macrophages abundantly found in obese body fat: the GPR120 receptor.(({{pubmed>long:20813258}})) The team showed that omega-3 fatty acids activate this macrophage receptor, resulting in broad anti-inflammatory effects. [[http://www.eurekalert.org/pub_releases/2010-09/uoc--wfo083010.php|Commenting about his work]], Olefsky said, "It's just an incredibly potent effect. The omega-3 fatty acids switch on the receptor, killing the inflammatory response."
 ===== Omega 3 fatty acids may cause disease =====
-  * **Mice given omega‐3's are more susceptible to pulmonary tuberculosis** – Bonilla //et al.// showed that  endogenous production of omega-3's in mice increases their susceptibility to tuberculosis, which they explained by noting the corresponding diminished activation and antimycobacterial responses in cells. The researchers concluded, "These data suggest that n‐3 PUFA–supplemented [dietary omega‐3 fatty acids] diets might have a detrimental effect on immunity to //M. tuberculosis// and raise concerns regarding the safety of omega‐3 dietary supplementation in humans."(({{pubmed>long:20053136}}))
+  * **Mice given omega‐3's are more susceptible to pulmonary tuberculosis** – Bonilla //et al.// showed that  transgenic mice engineered to produce omega-3's endogenously (internally) increased their susceptibility to tuberculosis, which they explained by noting the corresponding reduction in antimycobacterial responses in cells. The researchers concluded, "These data suggest that n‐3 PUFA–supplemented [dietary omega‐3 fatty acids] diets might have a detrimental effect on immunity to //M. tuberculosis// and raise concerns regarding the safety of omega‐3 dietary supplementation in humans."(({{pubmed>long:20053136}}))

home/othertreatments/efas.txt · Last modified: 09.14.2022 by 127.0.0.1