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home:othertreatments:efas [09.04.2010] – paulalberthome:othertreatments:efas [05.02.2011] – external edit 127.0.0.1
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   * **EPA and DHA switch off a key receptor responsible for innate immunity in fat cells.**  Olefsky and colleagues identified a key receptor on macrophages abundantly found in obese body fat: the GPR120 receptor.(({{pubmed>long:20813258}})) The team showed that omega-3 fatty acids activate this macrophage receptor, resulting in broad anti-inflammatory effects. [[http://www.eurekalert.org/pub_releases/2010-09/uoc--wfo083010.php|Commenting about his work]], Olefsky said, "It's just an incredibly potent effect. The omega-3 fatty acids switch on the receptor, killing the inflammatory response."   * **EPA and DHA switch off a key receptor responsible for innate immunity in fat cells.**  Olefsky and colleagues identified a key receptor on macrophages abundantly found in obese body fat: the GPR120 receptor.(({{pubmed>long:20813258}})) The team showed that omega-3 fatty acids activate this macrophage receptor, resulting in broad anti-inflammatory effects. [[http://www.eurekalert.org/pub_releases/2010-09/uoc--wfo083010.php|Commenting about his work]], Olefsky said, "It's just an incredibly potent effect. The omega-3 fatty acids switch on the receptor, killing the inflammatory response."
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 +  * **Fish oil-fed mice have impaired resistance to influenza infection.** 
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 +<blockquote>Although fish oil-fed mice had lower lung inflammation compared with controls, fish oil feeding also resulted in a 40% higher mortality rate, a 70% higher lung viral load at d 7 post infection, and a prolonged recovery period following infection.... Additionally, lungs of infected fish oil-fed mice had significantly fewer CD8+ T cells and decreased mRNA expression of macrophage inflammatory protein-1-alpha, tumor necrosis factor-alpha, and interleukin-6. These results suggest that the antiinflammatory properties of fish oil feeding can alter the immune response to influenza infection, resulting in increased morbidity and mortality.
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 +//**Schwerbrock** et al.//(({{pubmed>long:19549756}}))</blockquote>
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 ===== Omega 3 fatty acids may cause disease ===== ===== Omega 3 fatty acids may cause disease =====
home/othertreatments/efas.txt · Last modified: 09.14.2022 by 127.0.0.1
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